2,5-Bis(methoxymethyl)furan

Base Information

• Chemical Name: 2,5-Bis(methoxymethyl)furan
• CAS No.: 18801-76-8
• Molecular Formula: C8H12O3
• Molecular Weight: 156.181
• DSSTox Substance ID: DTXSID40506011
• Nikkaji Number: J3.299.666C
• Wikidata: Q82361546
• Mol file: 18801-76-8.mol

Synonyms:2,5-Bis(methoxymethyl)furan;18801-76-8;Furan, 2,5-bis(methoxymethyl)-;2,5-bis-methoxymethyl-furan;SCHEMBL55096;DTXSID40506011

Chemical Property of 2,5-Bis(methoxymethyl)furan

Chemical Property:

• XLogP3: 0.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 156.078644241
• Heavy Atom Count: 11
• Complexity: 93.5

Purity/Quality:

99.3% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC1=CC=C(O1)COC

Technology Process of 2,5-Bis(methoxymethyl)furan

There total 4 articles about 2,5-Bis(methoxymethyl)furan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 28.4%

methanol (67-56-1) + 5-hydroxymethyl-2-furfuraldehyde (67-47-0) → 2,5-bis-(hydroxymethyl)furan (1883-75-6) + [5-(methoxymethyl)furan-2-yl]methanol (934-93-0) + 2,5-furandimethanol dimethyl ether (18801-76-8)

Guidance literature:

With hydrogen; at 120 ℃; under 15001.5 Torr; Temperature; Autoclave;

DOI:10.1039/c7gc03072j

Reference yield: 17.6%

methanol (67-56-1) + 5-hydroxymethyl-2-furfuraldehyde (67-47-0) → 2,5-bis-(hydroxymethyl)furan (1883-75-6) + 2,5-furandimethanol dimethyl ether (18801-76-8)

Guidance literature:

With BaO-ZrO₂/SBA-15; at 100 ℃; for 2.5h; Autoclave;

Reference yield:

5-hydroxymethyl-2-furfuraldehyde (67-47-0) → 2,5-dimethyltetrahydrofuran (1003-38-9) + 2,5-dimethylfuran (625-86-5) + 2-(methoxymethyl)-5-methylfuran (18091-23-1) + [5-(methoxymethyl)furan-2-yl]methanol (934-93-0) + 2,5-furandimethanol dimethyl ether (18801-76-8)

Guidance literature:

With hydrogen; In methanol; at 220 ℃; for 6h; under 37503.8 Torr;

DOI:10.1002/cssc.201402095

upstream raw materials:

furfural

methanol

5-(ethoxymethyl)furfural

5-hydroxymethyl-2-furfuraldehyde