(1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine

Base Information

Chemical Name:(1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine
CAS No.:189396-84-7
Molecular Formula:C10H8F5NO
Molecular Weight:253.172
Hs Code.:
DSSTox Substance ID:DTXSID70578908
Nikkaji Number:J861.610H,J2.498.500H

Synonyms:189396-84-7;(1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine;DTXSID70578908

Suppliers and Price of (1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of (1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:253.05260469
Heavy Atom Count:17
Complexity:268

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N=CC(C(F)(F)F)(F)F

Technology Process of (1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine

There total 1 articles about (1E)-2,2,3,3,3-Pentafluoro-N-(4-methoxyphenyl)propan-1-imine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 337-28-0
1-ethoxy-2,2,3,3,3-pentafluoro-propan-1-ol

: 104-94-9
4-methoxy-aniline

: 189396-84-7
C₁₀H₈F₅NO

Guidance literature:: With toluene-4-sulfonic acid; In toluene; for 1.5h; Reflux; Inert atmosphere; Dean-Stark;
DOI:10.1021/acs.joc.8b01743

Reference yield: 80.0%

: 189396-84-7
C₁₀H₈F₅NO

: 76862-09-4
methyl N-(4-chlorobenzylidene)glycinate

: 1428259-75-9
(2R,4R,5R)-methyl 2-(4-chlorophenyl)-1-(4-methoxyphenyl)-5-(perfluoroethyl)-imidazolidine-4-carboxylate

Guidance literature:: With tetrakis(acetonitrile)copper(I)tetrafluoroborate; C₂₅H₂₅FeOP; triethylamine; In diethyl ether; at -20 ℃; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c3cc43025a DOI:10.1039/c3cc43025a

Reference yield: 26.0%

: 189396-84-7
C₁₀H₈F₅NO

: 123-38-6
propionaldehyde

: 1199944-71-2
(2R,3S)-4,4,5,5,5-pentafluoro-3-(4-methoxyphenylamino)-2-methylpentan-1-ol

Guidance literature:: C₁₀H₈F₅NO; With (2S)-2-{diphenyl[(trimethylsilyl)oxy]methyl}pyrrolidine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 0.25h; Inert atmosphere;

propionaldehyde; In 1-methyl-pyrrolidin-2-one; at -20 - 0 ℃; for 72h; Inert atmosphere;

With sodium tetrahydroborate; In methanol; at 0 ℃; for 3h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;
DOI:10.1002/ejoc.200900509