1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-

Base Information

Chemical Name:1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-
CAS No.:189509-25-9
Molecular Formula:C₁₅H₁₈O₃
Molecular Weight:246.306
Hs Code.:
DSSTox Substance ID:DTXSID30448911

Synonyms:1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-;189509-25-9;DTXSID30448911

Suppliers and Price of 1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of 1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:246.125594432
Heavy Atom Count:18
Complexity:297

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CC2(CCC1=O)CCOC(O2)C3=CC=CC=C3

Technology Process of 1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl-

There total 4 articles about 1,3-Dioxaspiro[5.5]undecan-9-one, 2-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 100-52-7
benzaldehyde

: 107389-91-3
4-hydroxy-4-(2-hydroxyethyl)cyclohexanone

: 189509-25-9
2-phenyl-1,3-dioxa-spiro[5.5]undecan-9-one

Guidance literature:: With toluene-4-sulfonic acid; at 20 ℃; for 2h;
DOI:10.1016/S0040-4020(97)00138-5

Reference yield:

: 4746-97-8
cyclohexanedione monoethylene ketal

: 189509-25-9
2-phenyl-1,3-dioxa-spiro[5.5]undecan-9-one

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / Zn / benzene / 1.5 h / 20 °C / Heating

2: 80 percent / LiAlH / diethyl ether / 2.8 h / 20 °C / Heating

3: water; Dowex 50X₈-100 (H⁺ form) / 24 h / 20 °C

4: 47 percent / p-TsOH / 2 h / 20 °C

With Dowex 50X₈-100 (H⁺ form); water; toluene-4-sulfonic acid; zinc; In diethyl ether; benzene; 1: Reformatsky reaction / 2: Reduction / 3: Hydrolysis / 4: Condensation;
DOI:10.1016/S0040-4020(97)00138-5

Reference yield:

: 189509-22-6
(8-hydroxy-1,4-dioxaspiro[4,5]dec-8-yl)-acetic acid ethyl ester

: 189509-25-9
2-phenyl-1,3-dioxa-spiro[5.5]undecan-9-one

Guidance literature:: Multi-step reaction with 3 steps

1: 80 percent / LiAlH / diethyl ether / 2.8 h / 20 °C / Heating

2: water; Dowex 50X₈-100 (H⁺ form) / 24 h / 20 °C

3: 47 percent / p-TsOH / 2 h / 20 °C

With Dowex 50X₈-100 (H⁺ form); water; toluene-4-sulfonic acid; In diethyl ether; 1: Reduction / 2: Hydrolysis / 3: Condensation;
DOI:10.1016/S0040-4020(97)00138-5