Aminoacetone

Base Information

• Chemical Name: Aminoacetone
• CAS No.: 298-08-8
• Molecular Formula: C3H7NO
• Molecular Weight: 73.0947
• European Community (EC) Number: 809-000-2
• UNII: ZB4ES38S4R
• DSSTox Substance ID: DTXSID10183939
• Nikkaji Number: J38.126H
• Wikipedia: Aminoacetone
• Wikidata: Q4545767
• Metabolomics Workbench ID: 38035
• Mol file: 298-08-8.mol

Synonyms:1-aminopropan-2-one

Chemical Property of Aminoacetone

Chemical Property:

• Melting Point: 130-131 °C
• Boiling Point: 120.6 °C at 760 mmHg
• PKA: 7.41±0.29(Predicted)
• Flash Point: 26.8 °C
• PSA: 43.09000
• Density: 0.926 g/cm³
• LogP: 0.23440
• XLogP3: -1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 1
• Exact Mass: 73.052763847
• Heavy Atom Count: 5
• Complexity: 42.2

Purity/Quality:

99% ^*data from raw suppliers

1-aminoacetone 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)CN

Technology Process of Aminoacetone

There total 2 articles about Aminoacetone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + N-acetonylphthalimide (3416-57-7) → glycine methyl ketone (298-08-8) + ammonium chloride + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

at 100 ℃;

Reference yield:

hydrogenchloride (7647-01-0,15364-23-5) + N-(2,2-bis-ethylmercapto-propyl)-phthalimide → glycine methyl ketone (298-08-8) + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5) + ethanethiol (75-08-1)

Guidance literature:

Reference yield: 56.0%

cyanic acid (420-05-3) + glycine methyl ketone (298-08-8) → 4-methyl-1,3-dihydro-imidazol-2-one (1192-34-3)

Guidance literature:

With hydrogenchloride;

DOI:10.1002/ardp.19953281005

upstream raw materials:

hydrogenchloride

N-acetonylphthalimide

Downstream raw materials:

2-mercapto-4-methylimidazole

hydroxy-2-propanone

5-methyl-2-phenyloxazole

4-methyl-2-phenyl-1H-imidazole