Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]-

Base Information

Chemical Name:Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]-
CAS No.:189950-07-0
Molecular Formula:C37H48ClN3O3S2
Molecular Weight:682.391
Hs Code.:

Acetamide,
2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct-
2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth
oxyphenyl)methyl]thio]ethyl]-

Synonyms:

Suppliers and Price of Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]-

There total 5 articles about Acetamide, 2-[[[(1R,2R,3S,5S)-3-(4-chlorophenyl)-8-methyl-8-azabicyclo[3.2.1]oct- 2-yl]methyl][2-[[(4-methoxyphenyl)methyl]thio]ethyl]amino]-N-[2-[[(4-meth oxyphenyl)methyl]thio]ethyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 185348-33-8
2-chloro N-[2-(4-methoxybenzyl-sulfanyl)-ethyl]acetamide

: 189950-05-8
[(1R,2R,3S,5S)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ylmethyl]-[2-(4-methoxy-benzylsulfanyl)-ethyl]-amine

: 189950-07-0
2-{[(1R,2R,3S,5S)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ylmethyl]-[2-(4-methoxy-benzylsulfanyl)-ethyl]-amino}-N-[2-(4-methoxy-benzylsulfanyl)-ethyl]-acetamide

Guidance literature:: With triethylamine; In acetonitrile; for 12h; Heating;
DOI:10.1021/jm960532j

Reference yield:

: 22876-64-8
2?((4?methoxybenzyl)thio)ethan?1?amine

: 189950-07-0
2-{[(1R,2R,3S,5S)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ylmethyl]-[2-(4-methoxy-benzylsulfanyl)-ethyl]-amino}-N-[2-(4-methoxy-benzylsulfanyl)-ethyl]-acetamide

Guidance literature:: Multi-step reaction with 2 steps

1: Et₃N / CH₂Cl₂ / -78 - 20 °C

2: 53 percent / Et₃N / acetonitrile / 12 h / Heating

With triethylamine; In dichloromethane; acetonitrile;
DOI:10.1021/jm960532j

Reference yield:

: 140633-58-5
3β-(4-Chlorophenyl)-tropane-2β-carboxylic acid

: 189950-07-0
2-{[(1R,2R,3S,5S)-3-(4-Chloro-phenyl)-8-methyl-8-aza-bicyclo[3.2.1]oct-2-ylmethyl]-[2-(4-methoxy-benzylsulfanyl)-ethyl]-amino}-N-[2-(4-methoxy-benzylsulfanyl)-ethyl]-acetamide

Guidance literature:: Multi-step reaction with 4 steps

1: (COCl)2 / CH₂Cl₂ / 1.5 h / Ambient temperature

2: Et₃N / CH₂Cl₂ / 6 h / Ambient temperature

3: 79 percent / BH₃*THF / 12 h / Heating

4: 53 percent / Et₃N / acetonitrile / 12 h / Heating

With borane-THF; oxalyl dichloride; triethylamine; In dichloromethane; acetonitrile;
DOI:10.1021/jm960532j