3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one

Base Information

Chemical Name:3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one
CAS No.:6322-63-0
Molecular Formula:C10H8ClNOS2
Molecular Weight:257.765
Hs Code.:
NSC Number:32125
DSSTox Substance ID:DTXSID70283560
Wikidata:Q82018169

Synonyms:6322-63-0;3-[(2-chlorophenyl)methyl]-2-sulfanylidene-1,3-thiazolidin-4-one;3-(2-chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one;NSC32125;SCHEMBL20339669;DTXSID70283560;MFCD00174840;NSC-32125;STL419031;AKOS000322111;NS-03947;BB 0217738

Suppliers and Price of 3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one

Chemical Property:

Vapor Pressure:4.71E-06mmHg at 25°C
Boiling Point:382.5°Cat760mmHg
Flash Point:185.1°C
Density:1.5g/cm³
XLogP3:3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:256.9735839
Heavy Atom Count:15
Complexity:285

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1C(=O)N(C(=S)S1)CC2=CC=CC=C2Cl

Technology Process of 3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one

There total 4 articles about 3-(2-Chlorobenzyl)-2-thioxo-1,3-thiazolidin-4-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 75-15-0,12122-00-8
carbon disulfide

: 13558-70-8
methyl N-(chloroacetyl)carbamate

: 89-97-4
2-CHLOROBENZYLAMINE

: 6322-63-0
3-(2-chlorobenzyl)-2-thioxothiazolidin-4-one

Guidance literature:: With triethylamine; In acetonitrile; at 20 ℃; for 0.166667h;
DOI:10.3390/molecules25051138

Reference yield: 60.0%

: 75-15-0,12122-00-8
carbon disulfide

: 105-36-2
ethyl bromoacetate

: 89-97-4
2-CHLOROBENZYLAMINE

: 6322-63-0
3-(2-chlorobenzyl)-2-thioxothiazolidin-4-one

Guidance literature:: 2-CHLOROBENZYLAMINE; With cyanomethanide; In acetonitrile; at -20 ℃; for 1h;

carbon disulfide; In acetonitrile; at -20 ℃; for 1h;

ethyl bromoacetate; In acetonitrile; at -20 - 20 ℃;
DOI:10.1080/17415990903191752

Reference yield: 27.0%

: 75-15-0,12122-00-8
carbon disulfide

: 79-11-8
chloroacetic acid

: 89-97-4
2-CHLOROBENZYLAMINE

: 6322-63-0
3-(2-chlorobenzyl)-2-thioxothiazolidin-4-one

Guidance literature:: carbon disulfide; 2-CHLOROBENZYLAMINE; In diethyl ether; at 0 ℃; for 1h; Inert atmosphere;

chloroacetic acid; In ethanol; at 100 ℃; for 5h;