13558-70-8

Usage

Uses

Used in Agricultural Industry:
Methyl chloroacetylcarbamate is used as a pesticide for controlling insect pests in crops due to its ability to inhibit the acetylcholinesterase enzyme, leading to the disruption of the insects' nervous systems and ultimately causing their death.
Methyl chloroacetylcarbamate is also used as a herbicide for managing unwanted plant growth in agricultural fields. Its mechanism of action targets the acetylcholinesterase enzyme in plants, disrupting their nervous system and leading to their controlled elimination, thus ensuring healthier crop growth and higher yields.

InChI:InChI=1/C4H6ClNO3/c1-9-4(8)6-3(7)2-5/h2H2,1H3,(H,6,7,8)

Upstream product

• 67-56-1 methanol 
• 4461-30-7 2-chloroacetylisocyanate 
• 79-37-8 oxalyl dichloride 
• 79-07-2 Chloroacetamide 
• 79-04-9 chloroacetyl chloride 
• 598-55-0 methyl carbamate 

Downstream Products

• 17823-27-7 2-(phenylimino)thiazolidin-4-one 
• 29163-28-8 Phenyl-phosphonodithioic acid S-(2-methoxycarbonylamino-2-oxo-ethyl) ester O-methyl ester 
• 34392-97-7 3-(4-methylbenzyl)-2-thioxothiazolidin-4-one 
• 6322-59-4 3-cyclohexyl-2-thioxo-1,3-thiazolidin-4-one 
• 1384879-41-7 3,3'-(1,4-phenylenebis(methylene))bis(2-thioxothiazolidin-4-one) 
• 1457-47-2 3-allylrhodanine 
• 21494-64-4 NSC-190633 
• 4807-55-0 3-Methyl-2-thioxo-thiazolidin-4-on 
• 3889-20-1 3-(2-phenylethyl)-2-thioxo-1,3-thiazolidin-4-one 
• 6322-62-9 3-(thiophen-2-ylmethyl)-2-thioxo-thiazolidin-4-one 
• 4703-95-1 3-(furan-2-ylmethyl)-2-sulfanylidene-1,3-thiazolidin-4-one 
• 6322-63-0 3-(2-chlorobenzyl)-2-thioxothiazolidin-4-one 
• 1089315-92-3 3-(3-chlorobenzyl)-2-thioxothiazolidin-4-one 

Relevant academic research and scientific papers

A concise approach to n-substituted rhodanines through a base-assisted one-pot coupling and cyclization process

An efficient approach to obtain functionalized rhodanines was developed through a base-assisted one-pot coupling and continuous cyclization of a primary amine, carbon disulfide, and methyl (2-chloroacetyl)carbamate. This conversion tolerates a broad range of functional groups and can be used to scale the preparation of N-substituted rhodanines in excellent yields.

SYNTHESIS OF IMIDE COMPOUNDS

The invention relates to a process for the production of an imide (1) (2) (3) via the enantioselective addition of an amine (2) to an alkene (3) wherein Y is OR, wherein R is alkyl or Bn, said process comprising: incubating Pd(OTf)2 with a phos

Methyl 6-(phenylsulfinyl)imidazo[1,2-a]pyridine-2-carbamate, a potent, new anthelmintic

A series of methyl imidazo[1,2-a]pyridine-2-carbamates was synthesized for anthelmintic testing. The preparation of this class of compounds was simplified by utilization of a novel one-step condensation of the appropriately substituted 2-aminopyridine with methyl chloroacetylcarbamate. The most potent compound, methyl 6-(phenylsulfinyl) imidazo[1,2-a] pyridine-2-carbamate, was orally effective against a broad range of helminths in sheep and cattle, at a dosage of 2.5 mg/kg. Limited trials in swine and dogs demonstrated anthelmintic activity at higher dosages. Limited observations in sheep and cattle indicated that, in both species, a single oral dose of 200 mg/kg was well tolerated.

Certain substituted imidazo [1,2-a] pyridines

Certain novel substituted imidazo [1,2-a] pyridines with a substituted amino group at the 2- or 3-position are active anthelmintic agents. The novel compounds are prepared from the appropriate substituted 2-aminopyridine precursor. Compositions which utilize said novel imidazo [1,2-a] pyridines as the active ingredient thereof for the treatment of helminthiasis are also disclosed.