Methyl chloroacetylcarbamate

Base Information

• Chemical Name: Methyl chloroacetylcarbamate
• CAS No.: 13558-70-8
• Molecular Formula: C4H6ClNO3
• Molecular Weight: 151.55
• Hs Code.: 2924199090
• Mol file: 13558-70-8.mol

Synonyms:Methyl (chloroacetyl)carbamate;Methyl N-(chloroacetyl)carbamate;Methyl N-(2-chloroacetyl)carbamate;Methyl N-chloroacetylcarbamate;Methyl (2-chloroacetyl)carbamate;

Chemical Property of Methyl chloroacetylcarbamate

Chemical Property:

• Melting Point: 149-151 °C
• Refractive Index: 1.447
• PKA: 7.24±0.46(Predicted)
• PSA: 55.40000
• Density: 1.313 g/cm³
• LogP: 0.49870

Purity/Quality:

97% ^*data from raw suppliers

Methyl N-(2-chloroacetyl)carbamate 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): R34:Causes burns.
• Hazard Codes: R34:Causes burns.
• Statements: R34:Causes burns.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S36/37/39:Wear suitabl

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Methyl chloroacetylcarbamate

There total 4 articles about Methyl chloroacetylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

methanol (67-56-1) + oxalyl dichloride (79-37-8) + Chloroacetamide (79-07-2) → methyl N-(chloroacetyl)carbamate (13558-70-8)

Guidance literature:

oxalyl dichloride; Chloroacetamide; In 1,2-dichloro-ethane; at 0 - 90 ℃; for 4h;

methanol; In 1,2-dichloro-ethane; at 0 ℃; for 0.0833333h;

DOI:10.3390/molecules25051138

Reference yield:

chloroacetyl chloride (79-04-9) + methyl carbamate (598-55-0) → methyl N-(chloroacetyl)carbamate (13558-70-8)

Guidance literature:

DOI:10.1039/jr9600000983

Reference yield:

methanol (67-56-1) + 2-chloroacetylisocyanate (4461-30-7) → methyl N-(chloroacetyl)carbamate (13558-70-8)

Guidance literature:

In benzene;

upstream raw materials:

chloroacetyl chloride

methyl carbamate

methanol

2-chloroacetylisocyanate

Downstream raw materials:

Phenyl-phosphonodithioic acid S-(2-methoxycarbonylamino-2-oxo-ethyl) ester O-methyl ester

2-(phenylimino)thiazolidin-4-one

Methyl N-(2-iminothiazolidin-3-ylacetyl)carbamate hydrochloride

methyl N-(2-iminothiazolyn-3-ylacetyl)carbamate