Phenol, p-(1-cyclohexen-1-yl)-

Base Information

• Chemical Name: Phenol, p-(1-cyclohexen-1-yl)-
• CAS No.: 709-08-0
• Molecular Formula: C12H14O
• Molecular Weight: 174.243
• Hs Code.: 2907199090
• DSSTox Substance ID: DTXSID50221127
• Nikkaji Number: J34.556C
• Wikidata: Q83098746
• Mol file: 709-08-0.mol

Synonyms:Phenol, p-(1-cyclohexen-1-yl)-;Cyclohexenyl-4-phenol;4-(1-Cyclohexen-1-yl)phenol;709-08-0;Phenol, 4-cyclohexenyl-;BRN 1866788;3-06-00-02747 (Beilstein Handbook Reference);p-(1-cyclohexenyl)-phenol;p-(cyclohexen-2-yl)phenol;SCHEMBL188943;Phenol, p-1-cyclohexen-1-yl-;DTXSID50221127;Phenol, 4-(1-cyclohexen-1-yl)-;LS-104279

Chemical Property of Phenol, p-(1-cyclohexen-1-yl)-

Chemical Property:

• Vapor Pressure: 0.000479mmHg at 25°C
• Boiling Point: 304.6°Cat760mmHg
• Flash Point: 137.1°C
• PSA: 20.23000
• Density: 1.086g/cm³
• LogP: 3.34960
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 174.104465066
• Heavy Atom Count: 13
• Complexity: 187

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(=CC1)C2=CC=C(C=C2)O

Technology Process of Phenol, p-(1-cyclohexen-1-yl)-

There total 20 articles about Phenol, p-(1-cyclohexen-1-yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 19.1%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + phenol (108-95-2,27073-41-2) → 2-(1-cyclohexenyl)cyclohexanone (1502-22-3) + 1-(4-hydroxyphenyl)-1-cyclohexene (709-08-0) + 1-(2-hydroxyphenyl)cyclohexene (13524-72-6) + 1,2,3,4,5,6,7,8,9,10,11,12-dodecahydrotriphenylene (1610-39-5) + 3,4-butano-2H-chromene-2-spirocyclohexane (95449-01-7) + 1,2,3,4,4a,9b-hexahydrodibenzo[b,d]furan (13524-79-3,151123-20-5)

Guidance literature:

With aluminium(III) phenoxide; at 180 ℃; for 10h; Product distribution; other temperature;

Reference yield: 0.8%

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + phenol (108-95-2,27073-41-2) → 1-(4-hydroxyphenyl)-1-cyclohexene (709-08-0) + 1-(2-hydroxyphenyl)cyclohexene (13524-72-6) + 3,4-butano-2H-chromene-2-spirocyclohexane (95449-01-7)

Guidance literature:

With aluminium(III) phenoxide; at 130 ℃;

Reference yield:

cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) + phenol (108-95-2,27073-41-2) → 1-(4-hydroxyphenyl)-1-cyclohexene (709-08-0) + 1-(2-hydroxyphenyl)cyclohexene (13524-72-6) + 1-(2-hydroxyphenyl)-1-(4-hydroxyphenyl)cyclohexane (71401-15-5) + p-cyclohexylphenol (1131-60-8)

Guidance literature:

With aluminium(III) phenoxide; at 200 - 250 ℃; under 7600 - 11400 Torr; Further byproducts given. Yields of byproduct given;

upstream raw materials:

1,1-bis(p-hydroxyphenyl)cyclohexane

cyclohexanone

phenol

p-Iodophenol

Downstream raw materials:

p-cyclohexylphenol

1-(4-methoxyphenyl)cyclohexene

4-[p-(1-cyclohexenyl)-phenoxy]-butyric acid

α-[p-(1-cyclohexenyl)-phenoxy]-undecanoic acid ethyl ester

Refernces

• 1、 Ewing, Tom A.,Van Noord, Aster,Paul, Caroline E.,Van Berkel, Willem J. H.. "A xylenol orange-based screening assay for the substrate specificity of flavin-dependent para-phenol oxidases". . . Retrieved 2018/01/18.
• 2、 Gron,Tinsley. "Tailoring aqueous solvents for organic reactions: Heck coupling reactions in high temperature water". . p. 227 - 230. Retrieved 2007/10/03.