tetra-O-methyl nordihydroguaiaretic acid

Base Information

Chemical Name:tetra-O-methyl nordihydroguaiaretic acid
CAS No.:5701-82-6
Molecular Formula:C22H30 O4
Molecular Weight:358.478
Hs Code.:
NSC Number:136955
DSSTox Substance ID:DTXSID10972502
Nikkaji Number:J490.487G
Wikidata:Q72509556
ChEMBL ID:CHEMBL492149
Mol file:5701-82-6.mol

Synonyms:4,4'-(2,3-dimethyl-1,4-butanediyl)bis-1,2-dimethoxybenzene;FW 358.2;FW-358.2;terameprocol;tetra-O-methyl-NDGA;tetra-O-methylnordihydroguaiaretic acid;tetramethoxynordihydroguaiaretic acid;TMNDGA

Suppliers and Price of tetra-O-methyl nordihydroguaiaretic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
Terameprocol
250mg
$ 418.00

TRC
Terameprocol
250mg
$ 125.00

Sigma-Aldrich
Terameprocol ≥98% (HPLC)
50 mg
$ 296.00

Sigma-Aldrich
Terameprocol ≥98% (HPLC)
10 mg
$ 75.40

Total 12 raw suppliers

Chemical Property of tetra-O-methyl nordihydroguaiaretic acid

Chemical Property:

Vapor Pressure:3.15E-11mmHg at 25°C
Boiling Point:458.5°Cat760mmHg
Flash Point:108.8°C
PSA：36.92000
Density:1.036g/cm³
LogP:4.77840
XLogP3:5.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:9
Exact Mass:358.21440943
Heavy Atom Count:26
Complexity:352

Purity/Quality:: Terameprocol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC(=C(C=C1)OC)OC)C(C)CC2=CC(=C(C=C2)OC)OC
Recent ClinicalTrials:A Pilot Study of EM-1421 for the Treatment of Cervical Intraepithelial Neoplasia

Technology Process of tetra-O-methyl nordihydroguaiaretic acid

There total 33 articles about tetra-O-methyl nordihydroguaiaretic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 278808-07-4
C₂₂H₂₈O₄

: 5701-82-6,24150-24-1,68930-18-7,119182-23-9
2,3-bis[(3,4-dimethoxyphenyl)methyl]butane

Guidance literature:: With hydrogen; platinum(IV) oxide; In ethyl acetate; for 1h;
DOI:10.1016/S0040-4039(01)01182-0

Reference yield: 88.25%

: 335327-93-0
1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethyl-2,3-butanediol

: 5701-82-6
1,4-bis(3,4-dimethoxyphenyl)-2,3-dimethylbutane

Guidance literature:: With trifluoroacetic acid; HSiPh₃; In dichloromethane; at 20 ℃; for 48.5h; Reagent/catalyst; Temperature; Inert atmosphere;