4440-92-0 Usage
Description
1,4-Butanedione, commonly known as diacetyl, is a colorless liquid chemical compound with a strong buttery odor. It is naturally found in some foods and is also produced synthetically. Widely used as a flavoring agent in food products such as butter, cheese, and caramel, diacetyl imparts a rich, creamy taste. However, it has been linked to respiratory issues and lung disease when inhaled in high concentrations, leading to its classification as a hazardous air pollutant. Consequently, many manufacturers are working to reduce or eliminate its use in their products.
Uses
Used in Food Industry:
1,4-Butanedione is used as a flavoring agent for its ability to impart a rich, creamy taste to food products such as butter, cheese, and caramel. Its natural presence in some foods and its synthetic production make it a popular choice for enhancing the flavor of various food items.
Used in Flavor Manufacturing Industry:
In the flavor manufacturing industry, 1,4-butanedione is used as a key ingredient in creating artificial flavors that mimic the taste of dairy products. Its strong buttery odor and taste make it an essential component in the development of flavor compounds used in a wide range of food products.
However, due to the potential health risks associated with inhalation of diacetyl, the industry is taking steps to reduce or eliminate its use. This includes exploring alternative flavoring agents and implementing safety measures to protect workers from long-term exposure to the chemical.
Check Digit Verification of cas no
The CAS Registry Mumber 4440-92-0 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,4,4 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 4440-92:
(6*4)+(5*4)+(4*4)+(3*0)+(2*9)+(1*2)=80
80 % 10 = 0
So 4440-92-0 is a valid CAS Registry Number.
4440-92-0Relevant articles and documents
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Ito,Y. et al.
, p. 1487 - 1493 (1977)
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Bioinspired total synthesis of tetrahydrofuran lignans by tandem nucleophilic addition/redox isomerization/oxidative coupling and cycloetherification reactions as key steps
Jagtap, Pratap R.,Císa?ová, Ivana,Jahn, Ullrich
supporting information, p. 750 - 755 (2018/02/09)
A very short three-step approach to trans,trans,trans-2,5-diaryl-3,4-dimethyltetrahydrofuran lignans is reported. The carbon skeleton is assembled in a single step based on an unprecedented tandem reaction consisting of 1,2-addition of aryllithium reagents to α,β-unsaturated aldehydes, ruthenium-catalyzed redox isomerization of the resulting alkoxides to enolates and their dimerization triggered by single electron oxidation. The resulting 2,3-dialkyl-1,4-diketones form with moderate to good d/l-diastereoselectivity and are transformed to the target tetrahydrofuran lignans by reduction and diastereoselective cycloetherification.
SCALABLE SYNTHETIC PROCESS FOR MAKING TERAMEPROCOL
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Page/Page column 30, (2010/04/03)
A manufacturing process for making terameprocol (1) which includes the following reaction scheme, wherein a first general reaction is the formation of a furan intermediate (39) and a second general reaction is the ring-reduction and ring-opening of the furan intermediate (39) to form the terameprocol (1)
