(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate

Base Information

Chemical Name:(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate
CAS No.:72835-26-8
Molecular Formula:C₈H₉NO₄
Molecular Weight:183.164
Hs Code.:
NSC Number:19630
DSSTox Substance ID:DTXSID90280990
Nikkaji Number:J801.044G
Wikidata:Q82014709
Pharos Ligand ID:8YXDMFK499GP
ChEMBL ID:CHEMBL1374426
Mol file:72835-26-8.mol

Synonyms:1-(propoxymethyl)maleimide;MIRA-1;NSC 19630

Suppliers and Price of (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
MIRA-1
10mg
$ 366.00

TRC
MIRA-1
50mg
$ 320.00

TRC
MIRA-1
10mg
$ 60.00

Tocris
MIRA-1
10
$ 119.00

Cayman Chemical
MIRA-1 ≥98%
10mg
$ 93.00

Cayman Chemical
MIRA-1 ≥98%
50mg
$ 391.00

ApexBio Technology
MIRA-1
10mg
$ 182.00

ApexBio Technology
MIRA-1
50mg
$ 763.00

American Custom Chemicals Corporation
MIRA-1 95.00%
5MG
$ 496.93

Ambeed
(2,5-Dioxo-2,5-dihydro-1H-pyrrol-1-yl)methylpropionate 97%
250mg
$ 87.00

Total 13 raw suppliers

Chemical Property of (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate

Chemical Property:

Vapor Pressure:0.00129mmHg at 25°C
Boiling Point:298.2°Cat760mmHg
Flash Point:134.1°C
PSA：63.68000
Density:1.307g/cm³
LogP:-0.24000
Storage Temp.:Store at +4°C
XLogP3:-0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:183.05315777
Heavy Atom Count:13
Complexity:264

Purity/Quality:

99%, ^*data from raw suppliers

MIRA-1 ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC(=O)OCN1C(=O)C=CC1=O
Uses The tumor suppressor gene, p53, is often mutated in most human cancers. MIRA-1 is a maleimide-derived molecule that can reactivate the mutant p53 leading to apoptosis in human tumor cells. In addition, the MIRA scaffold is an attractive lead for developing anticancer drugs that target mutant p53.

Technology Process of (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate

There total 2 articles about (2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)methyl propionate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: