2,2-Diethoxyacetamide

Base Information

• Chemical Name: 2,2-Diethoxyacetamide
• CAS No.: 61189-99-9
• Molecular Formula: C6H13NO3
• Molecular Weight: 147.174
• Hs Code.: 2924199090
• European Community (EC) Number: 262-647-7
• NSC Number: 363000
• UNII: ZN8XXW4Z7U
• DSSTox Substance ID: DTXSID90210075
• Nikkaji Number: J268.407A
• Wikidata: Q72468863
• Mol file: 61189-99-9.mol

Synonyms:2,2-Diethoxyacetamide;61189-99-9;Acetamide, 2,2-diethoxy-;EINECS 262-647-7;NSC-363000;Acetamide,2,2-diethoxy-;Glyoxylic amide diethyl acetal;diethoxyacetamide;NSC363000;ZN8XXW4Z7U;Glyoxylamide, diethyl acetal;SCHEMBL559406;2,2-Diethoxyacetamide, 97%;DTXSID90210075;BBL027994;MFCD00044023;STL146617;AKOS005721176;CS-W016347;NSC 363000;AS-30250;FT-0640731;A868788;1-METHYL-1-CYCLOHEXANECARBOXYLICACIDCHLORIDE

Chemical Property of 2,2-Diethoxyacetamide

Chemical Property:

• Appearance/Colour: off-white crystalline powder
• Vapor Pressure: 0.134mmHg at 25°C
• Melting Point: 76-78 °C(lit.)
• Refractive Index: 1.434
• Boiling Point: 217.3 °C at 760 mmHg
• Flash Point: 84.7 °C
• PSA: 61.55000
• Density: 1.04 g/cm³
• LogP: 0.57110
• Storage Temp.: 2-8°C
• XLogP3: -0.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 147.08954328
• Heavy Atom Count: 10
• Complexity: 99.2

Purity/Quality:

97% ^*data from raw suppliers

2,2-Diethoxyacetamide 97% ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(C(=O)N)OCC

Technology Process of 2,2-Diethoxyacetamide

There total 4 articles about 2,2-Diethoxyacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Ethyl diethoxyacetate (6065-82-3) → diethoxyacetamide (61189-99-9)

Guidance literature:

With ammonia; In ethanol; for 48h; Ambient temperature;

DOI:10.1246/bcsj.58.352

Reference yield:

ethanol (64-17-5) + hydrogen cyanide (74-90-8) → diethoxyacetamide (61189-99-9)

Guidance literature:

With hydrogenchloride;

Reference yield:

ethanol (64-17-5) + ethyl 2,2-diethoxyethanimidate (71648-28-7) → 2,2-diethoxyacetonitrile (6136-93-2) + diethoxyacetamide (61189-99-9) + pentaethoxyethane (58995-69-0) + Ethyl diethoxyacetate (6065-82-3)

Guidance literature:

DOI:10.1111/j.1447-0756.2000.tb01325.x

upstream raw materials:

ethanol

hydrogen cyanide

ethyl 2,2-diethoxyethanimidate

Ethyl diethoxyacetate

Downstream raw materials:

2,2-diethoxyacetonitrile

2,2-diethoxy-ethanamine

N-(2,3-Dimethoxybenzyl)diethoxyacetamide

ethyl 2,2-diethoxyethanimidate