(1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole

Base Information

Chemical Name:(1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole
CAS No.:194805-14-6
Molecular Formula:C28H24BrN
Molecular Weight:454.409
Hs Code.:
European Community (EC) Number:606-320-2
Mol file:194805-14-6.mol

Synonyms:194805-14-6;(R)-5-Bromo-1-methyl-2-tritylisoindoline;5-bromo-1-methyl-2-trityl-1,3-dihydroisoindole;SCHEMBL6669633;(1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole;HUWRJTHKCYGECM-UHFFFAOYSA-N;BCP27758;bromo-1-methyl-2-trityl-isoindoline;1H-Isoindole, 5-bromo-2,3-dihydro-1-methyl-2-(triphenylmethyl)-, (1R)-;(+)-5-bromo-1-methyl-2-trityliso-indoline;(1R)-5-bromo-1-methyl-2-trityl-isoindoline

Suppliers and Price of (1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
(R)-5-Bromo-1-methyl-2-tritylisoindoline 95%
100g
$ 1138.00

Total 27 raw suppliers

Chemical Property of (1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole

Chemical Property:

Vapor Pressure:2E-10mmHg at 25°C
Boiling Point:507.6oC at 760 mmHg
PKA:4.73±0.40(Predicted)
Flash Point:260.8oC
PSA：3.24000
Density:1.294g/cm3
LogP:7.25570
XLogP3:7.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:453.10921
Heavy Atom Count:30
Complexity:497

Purity/Quality:

99% ^*data from raw suppliers

(R)-5-Bromo-1-methyl-2-tritylisoindoline 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1C2=C(CN1C(C3=CC=CC=C3)(C4=CC=CC=C4)C5=CC=CC=C5)C=C(C=C2)Br

Technology Process of (1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole

There total 8 articles about (1R)-5-Bromo-1-methyl-2-(triphenylmethyl)-2,3-dihydro-1H-isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 223595-22-0
5-bromo-2-{(1R)-1-[(2,2-dimethylpropanoyl)amino]ethyl}benzyl acetate

: 76-83-5
trityl chloride

: 107-21-1
ethylene glycol

: 124-63-0
methanesulfonyl chloride

: 194805-14-6
(+)-(R)-5-bromo-1-methyl-2-(triphenylmethyl)isoindoline

Guidance literature:: 5-bromo-2-{(1R)-1-[(2,2-dimethylpropanoyl)amino]ethyl}benzyl acetate; With sodium hydroxide; tetrabutylammomium bromide; In water; toluene; at 35 ℃; for 1h;

methanesulfonyl chloride; With triethylamine; at 10 ℃; for 0.666667h;

trityl chloride; ethylene glycol; With hydrogenchloride; sodium hydroxide; tetrabutylammomium bromide; triethylamine; more than 3 stages;

Reference yield:

: (1R)-5-bromo-1-methyl-2,3-dihydro-1H-isoindole hydrochloride

: 76-83-5
trityl chloride

: 194805-14-6
(+)-(R)-5-bromo-1-methyl-2-(triphenylmethyl)isoindoline

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃; for 2h;

Reference yield:

: 223595-15-1
(R)-5-bromo-2-(2,2-dimethylpropanoyl)-1-methyl-isoindoline

: 76-83-5
trityl chloride

: 194805-14-6
(+)-(R)-5-bromo-1-methyl-2-(triphenylmethyl)isoindoline

Guidance literature:: (R)-5-bromo-2-(2,2-dimethylpropanoyl)-1-methyl-isoindoline; With hydrogenchloride; for 5h; Heating / reflux;

trityl chloride; With triethylamine; In dichloromethane; at 20 ℃; for 1h;