1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis-

Base Information

• Chemical Name: 1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis-
• CAS No.: 20176-55-0
• Molecular Formula: C18H18O3
• Molecular Weight: 282.339
• DSSTox Substance ID: DTXSID20443516
• Mol file: 20176-55-0.mol

Synonyms:1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis-;4-propionylphenyl ether;20176-55-0;SCHEMBL11052292;DTXSID20443516;RBCFVLWFDATRFV-UHFFFAOYSA-N;1-[4-(4-propionylphenoxy)phenyl]-1-propanone

Chemical Property of 1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis-

Chemical Property:

• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 282.125594432
• Heavy Atom Count: 21
• Complexity: 314

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC(=O)C1=CC=C(C=C1)OC2=CC=C(C=C2)C(=O)CC

Technology Process of 1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis-

There total 1 articles about 1-Propanone, 1,1'-(oxydi-4,1-phenylene)bis- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

diphenylether (101-84-8) + propionyl chloride (79-03-8) → bis-(4-propionyl-phenyl)-ether (20176-55-0)

Guidance literature:

With aluminium trichloride; In dichloromethane; at -20 - 0 ℃; for 3h;

DOI:10.1002/(SICI)1099-1395(1998110)11:11<825::AID-POC73>3.0.CO;2-U

Reference yield: 99.7%

bis-(4-propionyl-phenyl)-ether (20176-55-0) → 1-{4-[4-(1-Hydroxy-propyl)-phenoxy]-phenyl}-propan-1-ol (203866-25-5)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; ethanol; for 1.5h; Ambient temperature;

DOI:10.1002/(SICI)1099-1395(1998110)11:11<825::AID-POC73>3.0.CO;2-U DOI:10.1021/jo972072n

Reference yield:

bis-(4-propionyl-phenyl)-ether (20176-55-0) → bis[4-(1-propenyl)phenyl] ether

Guidance literature:

Multi-step reaction with 2 steps

1: 99.7 percent / sodium borohydride / ethanol; tetrahydrofuran / 1.5 h / Ambient temperature

2: pyridine, phosphorus oxychloride / 2 h / Heating

With pyridine; sodium tetrahydroborate; trichlorophosphate; In tetrahydrofuran; ethanol;

DOI:10.1021/jo972072n

upstream raw materials:

diphenylether

propionyl chloride

Downstream raw materials:

4,4'-oxybis

1-{4-[4-(1-Hydroxy-propyl)-phenoxy]-phenyl}-propan-1-ol

bis[4-(1-propenyl)phenyl] ether

methyl 4,4'-oxybis