2-Butenoic acid, 4-oxo-4-phenyl-, ethyl ester, (Z)-

Base Information

• Chemical Name: 2-Butenoic acid, 4-oxo-4-phenyl-, ethyl ester, (Z)-
• CAS No.: 20908-27-4
• Molecular Formula: C12H12O3
• Molecular Weight: 204.225
• Mol file: 20908-27-4.mol

Synonyms:4-oxo-4-phenyl-cis-crotonic acid ethyl ester;(Z)-ethyl-4-oxo-4-phenyl-2-butenoate;(Z)-4-Oxo-4-phenyl-but-2-enoic acid ethyl ester;4-Oxo-4-phenyl-cis-crotonsaeure-aethylester;ethyl 3-benzoylacrylate;

Chemical Property of 2-Butenoic acid, 4-oxo-4-phenyl-, ethyl ester, (Z)-

Chemical Property:

• Melting Point: 54 °C
• PSA: 43.37000
• LogP: 1.98860

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Butenoic acid, 4-oxo-4-phenyl-, ethyl ester, (Z)-

There total 30 articles about 2-Butenoic acid, 4-oxo-4-phenyl-, ethyl ester, (Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

carbon monoxide (201230-82-2) + Phenyl triflate (17763-67-6) + ethyl acrylate (140-88-5,9003-32-1) → ethyl 3-benzoyl acrylate (15121-89-8,20908-27-4,17450-56-5)

Guidance literature:

With palladium diacetate; caesium carbonate; In water; at 35 - 95 ℃; under 3750.38 Torr; Schlenk technique; Inert atmosphere;

DOI:10.1039/c8cc00324f

Reference yield: 81.0%

1-phenyl-2-hydroxyethanone (582-24-1) + 2,3-dimethyl-buta-1,3-diene (513-81-5) + ethyl (triphenylphosphoranylidene)acetate (1099-45-2) → ethyl 3-benzoyl acrylate (15121-89-8,20908-27-4,17450-56-5)

Guidance literature:

With sodium acetate; In toluene; for 6h; Reflux;

DOI:10.1016/j.tetlet.2010.10.121

Reference yield: 76.0%

(E)-4-Hydroxy-4-phenyl-but-2-enoic acid ethyl ester → ethyl 3-benzoyl acrylate (15121-89-8,20908-27-4,17450-56-5)

Guidance literature:

With 3,6-bis(triphenylphosphonium)cyclohexene dichromate; In acetonitrile; for 2h; Heating;

DOI:10.1080/10426500600634715

upstream raw materials:

ethanol

3-benzoylacrylic acid

4,4-Dimethoxy-4-phenyl-crotonsaeure-aethylester

4-phenyl-2-hydroxy-4-oxobutyric acid ethyl ester

Downstream raw materials:

phenacyl-succinic acid

2-(diethoxyphosphoryl)-4-oxo-4-phenylbutyric acid ethyl ester

C₂₂H₂₁ClO₄

C₂₃H₂₄O₅