1H-Pyrazolo[3,4-c]pyridazin-3-amine

Base Information

• Chemical Name: 1H-Pyrazolo[3,4-c]pyridazin-3-amine
• CAS No.: 2125-94-2
• Molecular Formula: C₅H₅N₅
• Molecular Weight: 135.128
• Hs Code.: 2933990090
• Mol file: 2125-94-2.mol

Synonyms:Pyrazolo-pyrazin;Pyrazolo<3,4-b>pyrazin;1H-Pyrazolo<3,4-b>pyrazin;3-Amino-1H-pyrazolo <3,4-c>-pyridazin;4,7-DIAZA-1H-INDAZOLE;

Chemical Property of 1H-Pyrazolo[3,4-c]pyridazin-3-amine

Chemical Property:

• PSA: 80.48000
• LogP: 0.51630

Purity/Quality:

99% ^*data from raw suppliers

1H-Pyrazolo[3,4-c]pyridazin-3-amine 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrazolo[3,4-c]pyridazin-3-amine

There total 7 articles about 1H-Pyrazolo[3,4-c]pyridazin-3-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-chloro-4-pyridazinecarbonitrile (1445-56-3) → 1H-pyrazolo[3,4-c]pyridazin-3-amine (2125-94-2)

Guidance literature:

With hydrazine hydrate; In butan-1-ol; at 130 ℃; for 20h;

Reference yield: 63.0%

5-chloro-1H-pyrazolo[4,3-e][1,2,4]triazin-3-amine (64613-37-2) → 1H-pyrazolo[3,4-c]pyridazin-3-amine (2125-94-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; sodium hydroxide; In methanol; at 50 ℃; for 1h;

Reference yield: 57.0%

5-amino-4-cyano-2,3-dihydrofuran-2,3-disulfonic acid disodium salt → 1H-pyrazolo[3,4-c]pyridazin-3-amine (2125-94-2)

Guidance literature:

With hydrazine hydrate; In ethanol; water; at 20 - 50 ℃; for 14h;

DOI:10.1002/jhet.5570400615

upstream raw materials:

3,6-dichloropyridazin-4-carboxylic acid

3,6-dichloropyridazine-4-carboxamide

3,6-dichloropyridazine-4-carbonitrile

5-chloro-1H-pyrazolo[4,3-e][1,2,4]triazin-3-amine