1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-

Base Information

Chemical Name:1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-
CAS No.:213776-03-5
Molecular Formula:C16H12F6O2
Molecular Weight:350.26
Hs Code.:
DSSTox Substance ID:DTXSID50445225
Nikkaji Number:J1.000.442J
Mol file:213776-03-5.mol

Synonyms:213776-03-5;1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-;DTXSID50445225;(1R,2R)-1,2-Bis[4-(trifluoromethyl)phenyl]-1,2-ethanediol

Suppliers and Price of 1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-

Chemical Property:

XLogP3:3.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:3
Exact Mass:350.07414859
Heavy Atom Count:24
Complexity:354

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(C(C2=CC=C(C=C2)C(F)(F)F)O)O)C(F)(F)F
Isomeric SMILES:C1=CC(=CC=C1[C@H]([C@@H](C2=CC=C(C=C2)C(F)(F)F)O)O)C(F)(F)F

Technology Process of 1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)-

There total 8 articles about 1,2-Ethanediol, 1,2-bis[4-(trifluoromethyl)phenyl]-, (1R,2R)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 42134-74-7
(E)-1,2-bis(4-trifluoromethylphenyl)ethene

: 213776-03-5
(R,R)-(+)-1,2-bis(4-trifluoromethylphenyl)ethane-1,2-diol

Guidance literature:: With methanesulfonamide; AD-mix-β; In water; tert-butyl alcohol; at 0 ℃; for 48h;
DOI:10.1016/j.tetlet.2005.01.086

Reference yield:

: 97-72-3
2-Methylpropionic anhydride

: 199166-26-2
(±)-1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-diol

: (1R,2R)-2-hydroxy-1,2-bis(4-(trifluoromethyl)phenyl)ethyl isobutyrate

: (1S,2S)-1,2-bis(4-(trifluoromethyl)phenyl)ethane-1,2-diyl bis(2-methylpropanoate)

: 213776-03-5
(R,R)-(+)-1,2-bis(4-trifluoromethylphenyl)ethane-1,2-diol

Guidance literature:: With (2S,3R)-3-isopropyl-2-phenyl-3,4-dihydro-2H-benzo[4,5]thiazolo[3,2-a]pyrimidine; N-ethyl-N,N-diisopropylamine; In chloroform; at 0 ℃; for 7h;
DOI:10.1055/s-0037-1610721

Reference yield:

: 42134-74-7
(E)-1,2-bis(4-trifluoromethylphenyl)ethene

: 213776-03-5
(R,R)-(+)-1,2-bis(4-trifluoromethylphenyl)ethane-1,2-diol

: (S,S)-(-)-1,2-bis(4-trifluoromethylphenyl)ethane-1,2-diol

Guidance literature:: With potassium carbonate; potassium hexacyanoferrate(III); potassium dioxotetrahydroxoosmate(VI); In water; toluene; tert-butyl alcohol; at 25 ℃; for 12h; Title compound not separated from byproducts.;
DOI:10.1016/j.tetlet.2008.05.016