2-(4-Trichloroacetylpiperazin-1-yl) anisole

Base Information

Chemical Name:2-(4-Trichloroacetylpiperazin-1-yl) anisole
CAS No.:219963-59-4
Molecular Formula:C13H15Cl3N2O2
Molecular Weight:337.633
Hs Code.:
DSSTox Substance ID:DTXSID00391980
Mol file:219963-59-4.mol

Synonyms:219963-59-4;2-(4-Trichloroacetylpiperazin-1-yl) anisole;2,2,2-trichloro-1-[4-(2-methoxyphenyl)piperazin-1-yl]ethanone;Piperazine, 1-(2-methoxyphenyl)-4-(trichloroacetyl)-;2,2,2-trichloro-1-(4-(2-methoxyphenyl)piperazin-1-yl)ethanone;SCHEMBL6184895;DTXSID00391980;ATXIDBZSKHBWEP-UHFFFAOYSA-N;STK416976;AKOS002377635;F84387;1-(2-Methoxyphenyl)-4-trichloroacetylpiperazine;AS-871/40318996;methyl 2-[4-(trichloroacetyl)-1-piperazinyl]phenyl ether;2,2,2-trichloro-1-[4-(2-methoxyphenyl)piperazin-1-yl]ethan-1-one;2,2,2-TRICHLORO-1-[4-(2-METHOXY-PHENYL)-PIPERAZIN-1-YL]-ETHANONE

Suppliers and Price of 2-(4-Trichloroacetylpiperazin-1-yl) anisole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-(4-Trichloroacetylpiperazin-1-yl) anisole

Chemical Property:

PSA：32.78000
LogP:2.71690
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:336.019911
Heavy Atom Count:20
Complexity:341

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC=C1N2CCN(CC2)C(=O)C(Cl)(Cl)Cl

Technology Process of 2-(4-Trichloroacetylpiperazin-1-yl) anisole

There total 3 articles about 2-(4-Trichloroacetylpiperazin-1-yl) anisole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 5464-78-8
1-(2-methoxyphenyl)piperazine hydrochloride

: 76-02-8
trifluoroacetyl chloride

: 219963-59-4
2,2,2-trichloro-1-(4-(2-methoxyphenyl)piperazin-1-yl)ethanone

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 4.16667h; Inert atmosphere;
DOI:10.1016/j.bmc.2011.06.090