DIMETHYL 2,4-DIMETHYLGLUTARATE

Base Information

• Chemical Name: DIMETHYL 2,4-DIMETHYLGLUTARATE
• CAS No.: 2121-68-8
• Molecular Formula: C9H16 O4
• Molecular Weight: 188.224
• Hs Code.: 2917190090
• Mol file: 2121-68-8.mol

Synonyms:Glutaricacid, 2,4-dimethyl-, dimethyl ester (6CI,7CI,8CI); Pentanedioic acid,2,4-dimethyl-, dimethyl ester (9CI); Dimethyl 2,4-dimethylglutarate; Dimethyl2,4-dimethylpentanedioate; Dimethyl a,a'-dimethylglutarate; NSC 76590

Chemical Property of DIMETHYL 2,4-DIMETHYLGLUTARATE

Chemical Property:

• Vapor Pressure: 0.231mmHg at 25°C
• Refractive Index: n20/D 1.425(lit.)
• Boiling Point: 207°Cat760mmHg
• Flash Point: 93.9°C
• PSA: 52.60000
• Density: 1.018g/cm³
• LogP: 0.99470

Purity/Quality:

99% ^*data from raw suppliers

Dimethyl2,4-Dimethylglutarate 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of DIMETHYL 2,4-DIMETHYLGLUTARATE

There total 3 articles about DIMETHYL 2,4-DIMETHYLGLUTARATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 46.0%

m-xylene (108-38-3,104809-90-7) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → 3-methylstyrene (100-80-1) + meso-2,3-dimethylsuccinic acid dimethyl ester (28306-68-5) + propanoic acid methyl ester (554-12-1) + dimethyl 2,4-dimethylpentanedioate (2121-68-8) + methyl 2-methyl-4-(3-tolyl)butyrate (38795-60-7) + 1,3-di(3-tolyl)propane (23937-94-2)

Guidance literature:

at 350 ℃; for 6h; Product distribution; steel autoclave, presence of di-tert-butyl peroxide at 170 deg C;

Reference yield: 25.0%

m-xylene (108-38-3,104809-90-7) + methacrylic acid methyl ester (80-62-6,114512-63-9,143476-91-9,25188-98-1,9011-14-7) → propanoic acid methyl ester (554-12-1) + dimethyl 2,4-dimethylpentanedioate (2121-68-8) + methyl 2-methyl-4-(3-tolyl)butyrate (38795-60-7) + 1,3-di(3-tolyl)propane (23937-94-2)

Guidance literature:

at 350 ℃; for 6h; Further byproducts given; steel autoclave;

Reference yield:

diazomethane (186581-53-3,908094-01-9,334-88-3) + 3,5-dimethyl-cyclohexanone (7214-52-0) → methyl 2-methylsuccinate (21307-96-0,22644-27-5,63163-08-6,1604-11-1) + dimethyl 2,4-dimethylpentanedioate (2121-68-8) + (2RS,4SR)-2,4-Dimethyladipinsaeure-dimethylester

Guidance literature:

With nitric acid; Yield given. Multistep reaction. Yields of byproduct given; 1.) water, 100 deg C, 15 min; 2.) methanol, ether, r.t.;

DOI:10.1002/hlca.19830660111

upstream raw materials:

diazomethane

3,5-dimethyl-cyclohexanone

m-xylene

methacrylic acid methyl ester

Downstream raw materials:

1,2-Dimethyl-r-1,c-2-cyclopropandicarbonsaeure-dimethylester

2,4-dimethylglutaric acid

DL-2,4-dimethylglutaric acid

Refernces

• 1、 Bassi,Joos,Gassmann,et al.. "On the structure elucidation of niphimycin. Part I. Purification and characterization of the niphimycins Iα and Iβ: Degradation by nitric acid". . p. 92 - 117. Retrieved 2007/10/02.