4,7-Methano-1H-indene-2,5-dicarboxylic acid, 3a,4,7,7a-tetrahydro-

Base Information

• Chemical Name: 4,7-Methano-1H-indene-2,5-dicarboxylic acid, 3a,4,7,7a-tetrahydro-
• CAS No.: 24305-09-7
• Molecular Formula: C₁₂H₁₂O₄
• Molecular Weight: 220.225
• Mol file: 24305-09-7.mol

Synonyms:Tricyclo[5.2.1.02,6]deca-3,8-diene-4,9-dicarboxylic Acid;

Chemical Property of 4,7-Methano-1H-indene-2,5-dicarboxylic acid, 3a,4,7,7a-tetrahydro-

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

3a,4,7,7a-Tetrahydro-4,7-methanoindene-2,5-dicarboxylicAcid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Uses: 3a,4,7,7a-Tetrahydro-4,7-methanoindene-2,5-dicarboxylic Acid is a useful synthetic intermediate. It is used as a mimic of a distorted β-D-mannopyranoside.

Technology Process of 4,7-Methano-1H-indene-2,5-dicarboxylic acid, 3a,4,7,7a-tetrahydro-

There total 6 articles about 4,7-Methano-1H-indene-2,5-dicarboxylic acid, 3a,4,7,7a-tetrahydro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2-monochlorophenol (95-57-8) → (3aS,4S,7R,7aR)-3a,4,7,7a-Tetrahydro-1H-4,7-methano-indene-2,5-dicarboxylic acid (24305-09-7,85027-86-7)

Guidance literature:

Mechanism; Irradiation; pH=8-13;

DOI:10.1016/S0040-4039(00)87163-4

Reference yield: 32.8%

carbon dioxide (124-38-9,18923-20-1) + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → Tricyclo<5,2,1,02,6>deca-3,8-dien-4,9-dicarbonsaeure (24305-09-7)

Guidance literature:

cyclopenta-1,3-diene; With sodium; In tetrahydrofuran;

carbon dioxide; In tetrahydrofuran; at -78 - 20 ℃;

DOI:10.1021/acs.chemmater.8b01703

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + cyclopenta-1,3-diene (542-92-7,25568-84-7,7313-32-8) → (3aS,4S,7R,7aR)-3a,4,7,7a-Tetrahydro-1H-4,7-methano-indene-2,5-dicarboxylic acid (24305-09-7,85027-86-7) + (3aR,4R,7R,7aR)-3,4,7,7a-Tetrahydro-4,7-methano-indene-3a,6-dicarboxylic acid

Guidance literature:

cyclopenta-1,3-diene; With n-butyllithium; In hexane; at -20 ℃;

carbon dioxide; In tetrahydrofuran; at -30 ℃;

In chloroform; at 20 ℃; for 2h;

DOI:10.1016/S0022-328X(99)00116-3

upstream raw materials:

carbon dioxide

cyclopenta-1,3-diene

2-monochlorophenol