3-(Benzyloxy)-4-methoxyphenylboronic acid

Base Information

Chemical Name:3-(Benzyloxy)-4-methoxyphenylboronic acid
CAS No.:243990-54-7
Molecular Formula:C14H15BO4
Molecular Weight:258.082
Hs Code.:2931900090
DSSTox Substance ID:DTXSID30442176
Nikkaji Number:J1.141.260B
Wikidata:Q82259306
Mol file:243990-54-7.mol

Synonyms:3-(BENZYLOXY)-4-METHOXYPHENYLBORONIC ACID;243990-54-7;(3-(Benzyloxy)-4-methoxyphenyl)boronic acid;(4-methoxy-3-phenylmethoxyphenyl)boronic acid;(3-(Benzyloxy)-4-methoxyphenyl)boronicacid;SCHEMBL4329673;DTXSID30442176;MFCD10696652;AKOS015893103;AB57844;BS-27759;CS-0150598;D94918;3-(benzyloxy)-4-methoxyphenylboronic acid, AldrichCPR

Suppliers and Price of 3-(Benzyloxy)-4-methoxyphenylboronic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(Benzyloxy)-4-methoxyphenylboronicacid
50mg
$ 55.00

TRC
3-(Benzyloxy)-4-methoxyphenylboronicacid
25mg
$ 45.00

SynChem
3-(BENZYLOXY)-4-METHOXYPHENYLBORONIC ACID 95%
1 g
$ 200.00

Crysdot
(3-(Benzyloxy)-4-methoxyphenyl)boronicacid 95+%
5g
$ 589.00

AOBChem
3-(Benzyloxy)-4-methoxyphenylboronicacid 97%
500mg
$ 145.00

American Custom Chemicals Corporation
(3-(BENZYLOXY)-4-METHOXYPHENYL)BORONIC ACID 95.00%
1G
$ 351.75

Alichem
(3-(Benzyloxy)-4-methoxyphenyl)boronicacid
5g
$ 504.00

AK Scientific
3-(Benzyloxy)-4-methoxyphenylboronicacid
250mg
$ 177.00

Total 20 raw suppliers

Chemical Property of 3-(Benzyloxy)-4-methoxyphenylboronic acid

Chemical Property:

Boiling Point:444.3±55.0 °C(Predicted)
PKA:8.48±0.10(Predicted)
PSA：58.92000
Density:1.21±0.1 g/cm3(Predicted)
LogP:0.95400
Storage Temp.:under inert gas (nitrogen or Argon) at 2-8°C
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:258.1063391
Heavy Atom Count:19
Complexity:256

Purity/Quality:

97% ^*data from raw suppliers

3-(Benzyloxy)-4-methoxyphenylboronicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:B(C1=CC(=C(C=C1)OC)OCC2=CC=CC=C2)(O)O

Technology Process of 3-(Benzyloxy)-4-methoxyphenylboronic acid

There total 9 articles about 3-(Benzyloxy)-4-methoxyphenylboronic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 121-43-7,63156-11-6
Trimethyl borate

: 78504-28-6
2-Benzyloxy-4-bromo-1-methoxybenzene

: 243990-54-7
(3-(benzyloxy)-4-methoxyphenyl)boronic acid

Guidance literature:: 2-Benzyloxy-4-bromo-1-methoxybenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 1h; Inert atmosphere;

Trimethyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 5h; Inert atmosphere;

With hydrogenchloride; In tetrahydrofuran; hexane; water; at -20 - 20 ℃; pH=2 - 3; Inert atmosphere;
DOI:10.1016/j.bmc.2017.01.050

Reference yield:

: 37942-01-1
5-bromo-2-methoxyphenol

: 243990-54-7
(3-(benzyloxy)-4-methoxyphenyl)boronic acid

Guidance literature:: Multi-step reaction with 2 steps

1.1: potassium carbonate / acetone / 0.08 h / Inert atmosphere

1.2: Inert atmosphere; Reflux

2.1: n-butyllithium / tetrahydrofuran; hexane / 1 h / -78 °C / Inert atmosphere

2.2: 5 h / -78 - 20 °C / Inert atmosphere

2.3: -20 - 20 °C / pH 2 - 3 / Inert atmosphere

With n-butyllithium; potassium carbonate; In tetrahydrofuran; hexane; acetone;
DOI:10.1016/j.bmc.2017.01.050

Reference yield:

: 2-(benzyloxy)-4-iodo-1-methoxybenzene

: 243990-54-7
(3-(benzyloxy)-4-methoxyphenyl)boronic acid

Guidance literature:: 2-(benzyloxy)-4-iodo-1-methoxybenzene; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.25h;

With Triisopropyl borate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 12h;

With hydrogenchloride; In tetrahydrofuran; hexane; at 0 ℃; pH=6.5;
DOI:10.1021/jm049622b