2,2-Dimethyloxan-4-ol

Base Information

• Chemical Name: 2,2-Dimethyloxan-4-ol
• CAS No.: 24945-13-9
• Molecular Formula: C7H14O2
• Molecular Weight: 130.187
• Hs Code.: 2932990090
• European Community (EC) Number: 832-383-2
• DSSTox Substance ID: DTXSID50406790
• Mol file: 24945-13-9.mol

Synonyms:2,2-dimethyloxan-4-ol;24945-13-9;2,2-Dimethyltetrahydropyran-4-ol;2,2-DIMETHYLTETRAHYDRO-2H-PYRAN-4-OL;2,2-Dimethyl-tetrahydro-pyran-4-ol;2H-Pyran-4-ol, tetrahydro-2,2-dimethyl-;MFCD01549685;2, 2-dimethyloxan-4-ol;SCHEMBL1371482;AMY9124;DTXSID50406790;BONHKCQIMVZXBV-UHFFFAOYSA-N;ZAA94513;AKOS005264554;SB36172;AS-42757;SY023965;2 pound not2-Dimethyltetrahydropyran-4-ol;CS-0180925;EN300-117852;Z1192342111

Chemical Property of 2,2-Dimethyloxan-4-ol

Chemical Property:

• Vapor Pressure: 0.0595mmHg at 25°C
• Boiling Point: 205.4oC at 760 mmHg
• Flash Point: 80.9oC
• PSA: 29.46000
• Density: 0.979g/cm3
• LogP: 0.93630
• Storage Temp.: 2-8°C
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 130.099379685
• Heavy Atom Count: 9
• Complexity: 99.1

Purity/Quality:

97% ^*data from raw suppliers

2,2-Dimethyltetrahydro-2H-pyran-4-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CC(CCO1)O)C

Technology Process of 2,2-Dimethyloxan-4-ol

There total 7 articles about 2,2-Dimethyloxan-4-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

2,2-dimethyltetrahydropyran-4-one (1194-16-7) → 2,2-dimethyltetrahydropyran-4-ol (24945-13-9)

Guidance literature:

With methanol; sodium tetrahydroborate; at 0 - 20 ℃; for 3h;

Reference yield: 43.0%

2,2-dimethyltetrahydropyran-4-one (1194-16-7) + methanol (67-56-1) → 2,2-dimethyltetrahydropyran-4-ol (24945-13-9) + 4-hydroxymethyl-2,2-dimethyltetrahydropyran-4-ol (109752-89-8)

Guidance literature:

for 12h; Irradiation;

DOI:10.1007/BF00954824

Reference yield:

4-hydroxymethyl-2,2-dimethyltetrahydropyran-4-ol (109752-89-8) → 2,2-dimethyltetrahydropyran-4-ol (24945-13-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaIO₄ / H₂O / 1 h

2: NaBH₄ / aq. ethanol

With sodium tetrahydroborate; sodium periodate; In ethanol; water;

DOI:10.1007/BF00954824

upstream raw materials:

homoalylic alcohol

acetone

2,2-dimethyltetrahydropyran-4-one

methanol

Downstream raw materials:

C₁₄H₂₀O₄S

C₁₄H₂₀O₄S

3-{4-[(2,2-dimethyltetrahydro-2H-pyran-4-yl)oxy]phenyl}-2-ethyl-5-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-6-propylpyrimidin-4(3H)-one