Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester

Base Information

Chemical Name:Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester
CAS No.:249507-22-0
Molecular Formula:C29H34N2O4S
Molecular Weight:506.666
Hs Code.:
Mol file:249507-22-0.mol

Synonyms:

Suppliers and Price of Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester

There total 1 articles about Carbamic acid, [(1S)-2-(methoxymethylamino)-2-oxo-1-[[(triphenylmethyl)thio]methyl]eth yl]-, 1,1-dimethylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: N-(tert-butoxycarbonyl)-S-trityl-D-cysteine

: 249507-22-0
(S)-N-methyl-N-methoxy-2-tert-butoxycarbonylamino-3-(triphenylmethylthio)propionamide

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 2.5h;
DOI:10.1021/ol052907d

Reference yield:

: 249507-22-0
(S)-N-methyl-N-methoxy-2-tert-butoxycarbonylamino-3-(triphenylmethylthio)propionamide

: 175357-57-0
tert-butyl (S)-(1-oxo-3-(tritylthio)propan-2-yl)carbamate

Guidance literature:: With diisobutylaluminium hydride; In toluene; at -78 ℃; for 0.25h;
DOI:10.1021/ol052907d

Reference yield:

: 249507-22-0
(S)-N-methyl-N-methoxy-2-tert-butoxycarbonylamino-3-(triphenylmethylthio)propionamide

: 878626-74-5
(2E)-(4S)-4-N-tert-butoxycarbonylamino-2-methyl-5-(triphenylmethylthio)-2-pentenoic acid allyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: DIBALH / toluene / 0.25 h / -78 °C

2: 1.96 g / toluene / 3 h / 20 °C

3: LiOH / 2-methyl-propan-2-ol; H₂O; tetrahydrofuran / 12 h / 20 °C

4: 502 mg / K₂CO₃ / dimethylformamide / 2 h / 20 °C

With lithium hydroxide; diisobutylaluminium hydride; potassium carbonate; In tetrahydrofuran; water; N,N-dimethyl-formamide; toluene; tert-butyl alcohol; 2: Wittig olefination;
DOI:10.1021/ol052907d