2-Hydroxyadipic acid

Base Information

Chemical Name:2-Hydroxyadipic acid
CAS No.:18294-85-4
Molecular Formula:C6H10O5
Molecular Weight:162.142
Hs Code.:2918199090
DSSTox Substance ID:DTXSID20864823
Nikkaji Number:J428.482H
Wikidata:Q27102177
Metabolomics Workbench ID:1971
Mol file:18294-85-4.mol

Synonyms:2-hydroxyadipic acid;2-hydroxyhexanedioic acid

Suppliers and Price of 2-Hydroxyadipic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
2-Hydroxyhexanedioicacid 97%
1g
$ 432.00

ChemScene
2-Hydroxyadipicacid ≥98.0%
1g
$ 1937.00

American Custom Chemicals Corporation
2-HYDROXYHEXANEDIOIC ACID 95.00%
5MG
$ 503.83

Total 27 raw suppliers

Chemical Property of 2-Hydroxyadipic acid

Chemical Property:

Vapor Pressure:4.04E-08mmHg at 25°C
Melting Point:151 °C
Refractive Index:1.512
Boiling Point:401.6°Cat760mmHg
PKA:3.77±0.21(Predicted)
Flash Point:210.8°C
PSA：94.83000
Density:1.413g/cm³
LogP:-0.31320
Storage Temp.:2-8°C
Solubility.:Methanol, Water
XLogP3:-0.6
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:5
Exact Mass:162.05282342
Heavy Atom Count:11
Complexity:153

Purity/Quality:

97% ^*data from raw suppliers

2-Hydroxyhexanedioicacid 97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(CC(C(=O)O)O)CC(=O)O
Uses 2-Hydroxyhexanedioic acid is an intermediate in the synthesis of 2-Hydroxyhexanedioic Acid Disodium Salt (H943015). Accumulation and excretion of 2-Hydroxyhexanedioic Acid (with 2-ketoadipic and 2-aminoadipic) in urine can be caused by 2-ketoadipic acidemia, probably without adverse phenotypic effects, due to deficiency of 2-ketoadipic dehydrogenase.

Technology Process of 2-Hydroxyadipic acid

There total 26 articles about 2-Hydroxyadipic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 2-acetoxyhexanedioic acid

: 18294-85-4,77252-44-9
2-hydroxyadipic acid

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water;
DOI:10.1002/chem.201100339

Reference yield: 38.0%

: 3184-35-8
2-oxohexanedioic acid

: 542-32-5
(R,S)-2-aminoadipic acid

: 18294-85-4,77252-44-9
2-hydroxyadipic acid

Guidance literature:: With water; ammonium formate; [Rh(pentamethylcyclopentadiene)(2,2'-bipyridine)H₂O]SO₄; at 80 ℃; for 1h; pH=4.5; Product distribution / selectivity;