4-methyl-N-quinolin-2-ylbenzenesulfonamide

Base Information

Chemical Name:4-methyl-N-quinolin-2-ylbenzenesulfonamide
CAS No.:25770-52-9
Molecular Formula:C16H14N2O2S
Molecular Weight:298.365
Hs Code.:
DSSTox Substance ID:DTXSID501322402
Nikkaji Number:J2.831.274A
ChEMBL ID:CHEMBL1401199
Mol file:25770-52-9.mol

Synonyms:25770-52-9;4-methyl-N-quinolin-2-ylbenzenesulfonamide;2-AMINOQUINOLINE-P-TOLUENESULFONAMIDE;4-METHYL-N-(QUINOLIN-2-YL)BENZENESULFONAMIDE;4-methyl-N-(quinolin-2-yl)benzene-1-sulfonamide;Oprea1_557930;MLS000850256;SCHEMBL3485583;CHEMBL1401199;XFJJGEIKODBFGJ-UHFFFAOYSA-N;DTXSID501322402;HMS2800J09;N-(2-Quinolyl)-p-toluenesulfonamide;4-methyl-N-quinolinylbenzenesulfonamide;CCG-241522;SMR000456274;4-methyl-N-(2-quinolinyl)benzenesulfonamide;FT-0709520;W-202086

Suppliers and Price of 4-methyl-N-quinolin-2-ylbenzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 9 raw suppliers

Chemical Property of 4-methyl-N-quinolin-2-ylbenzenesulfonamide

Chemical Property:

Boiling Point:492.1±47.0 °C(Predicted)
PKA:7.31±0.30(Predicted)
PSA：67.44000
Density:1.342±0.06 g/cm3 (20 oC 760 Torr)
LogP:4.49780
XLogP3:3.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:298.07759887
Heavy Atom Count:21
Complexity:438

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)NC2=NC3=CC=CC=C3C=C2

Technology Process of 4-methyl-N-quinolin-2-ylbenzenesulfonamide

There total 8 articles about 4-methyl-N-quinolin-2-ylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 1613-37-2
Quinoline N-oxide

: 70-55-3
toluene-4-sulfonamide

: 25770-52-9
4-methyl-N-(quinolin-2-yl)benzenesulfonamide

Guidance literature:: With [bis(acetoxy)iodo]benzene; triphenylphosphine; In acetonitrile; at 80 ℃; for 12h; Reagent/catalyst; Solvent; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02922

Reference yield: 97.0%

: 1613-37-2
Quinoline N-oxide

: 55962-05-5
[N-(p-tolylsulfonyl)imino]phenyliodinane

: 25770-52-9
4-methyl-N-(quinolin-2-yl)benzenesulfonamide

Guidance literature:: With triphenylphosphine; In acetonitrile; at 80 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.7b02922

Reference yield: 65.0%

: 2005-43-8
2-bromoquinoline

: 70-55-3
toluene-4-sulfonamide

: 25770-52-9
4-methyl-N-(quinolin-2-yl)benzenesulfonamide

Guidance literature:: With copper(l) iodide; potassium carbonate; (1S,2S)-N,N'-dimethyl-1,2-diaminocyclohexane; In N,N-dimethyl-formamide; at 20 - 100 ℃;
DOI:10.1021/ol100263r