1-Naphthylglycolic acid

Base Information

• Chemical Name: 1-Naphthylglycolic acid
• CAS No.: 6341-54-4
• Molecular Formula: C12H10 O3
• Molecular Weight: 202.21
• Hs Code.: 2918199090
• NSC Number: 46719
• DSSTox Substance ID: DTXSID10286631
• Mol file: 6341-54-4.mol

Synonyms:1-Naphthylglycolic acid;6341-54-4;2-hydroxy-2-naphthalen-1-ylacetic acid;1-Naphthaleneglycolic acid;2-Hydroxy-2-(naphthalen-1-yl)acetic acid;NIOSH/QJ7160000;Acide alpha-naphthylphenylhydroxyacetique;alpha-Hydroxy-1-naphthaleneglycolic acid;1-Naphthaleneglycolic acid, alpha-hydroxy-;QJ71600000;Acide alpha-naphthylphenylhydroxyacetique [French];napthalene-2-oxyacetic acid;SCHEMBL1826565;SCHEMBL14376212;DTXSID10286631;AXSZGQWPAAHKDH-UHFFFAOYSA-N;NSC46719;MFCD14602012;NSC-46719;2-Hydroxy-2-(1-naphthyl)acetic Acid;AKOS010489121;SY314635;FT-0723227;EN300-1867164

Chemical Property of 1-Naphthylglycolic acid

Chemical Property:

• Vapor Pressure: 4.04E-08mmHg at 25°C
• Melting Point: 80 °C
• Boiling Point: 428.9°C at 760 mmHg
• PKA: 3.42±0.30(Predicted)
• Flash Point: 227.3°C
• PSA: 57.53000
• Density: 1.354g/cm³
• LogP: 1.95780
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 202.062994177
• Heavy Atom Count: 15
• Complexity: 239

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC=C2C(C(=O)O)O

Technology Process of 1-Naphthylglycolic acid

There total 7 articles about 1-Naphthylglycolic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1-naphthalenecarboxylic acid (86-55-5) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With methyl iodide; sodium sulfide; In water; isopropyl alcohol; at 20 ℃; for 20h;

DOI:10.1246/bcsj.61.4151

Reference yield:

carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1-naphthalenecarboxylic acid (86-55-5) + ethyl 1-naphthoate (3007-97-4) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With calcium hydroxide; dicobalt octacarbonyl; methyl iodide; In ethanol; water; for 20h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00388a060

Reference yield:

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1'-naphthacetophenone (941-98-0) + ethyl 1-naphthoate (3007-97-4) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With calcium hydroxide; dicobalt octacarbonyl; methyl iodide; In ethanol; water; for 20h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00388a060

upstream raw materials:

naphthalene

acetyl chloride

ethanol

carbon monoxide

Downstream raw materials:

1-naphthaldehyde

C₁₉H₁₄F₃NO₂

methoxy(naphthalen-1-yl)acetic acid

(R)-Hydroxy-(naphthyl-⁽¹⁾)-essigsaeure-((1R)-menthylester)

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 6341-54-4 1-Naphthaleneglycolic acid

Send

Send

Metric Ton KG G Pound L ML

Send

Send