1-NAPHTHOYLFORMIC ACID

Base Information

• Chemical Name: 1-NAPHTHOYLFORMIC ACID
• CAS No.: 26153-26-4
• Molecular Formula: C12H8 O3
• Molecular Weight: 200.194
• Hs Code.: 2918300090
• Mol file: 26153-26-4.mol

Synonyms:1-Naphthaleneglyoxylicacid (7CI,8CI); 1-Naphthylglyoxylic acid; a-Naphthyloxoacetic acid

Chemical Property of 1-NAPHTHOYLFORMIC ACID

Chemical Property:

• Vapor Pressure: 3.31E-06mmHg at 25°C
• Melting Point: 112-113 °C
• Refractive Index: 1.666
• Boiling Point: 372.4°C at 760 mmHg
• PKA: 2.07±0.54(Predicted)
• Flash Point: 193.2°C
• PSA: 54.37000
• Density: 1.337g/cm³
• LogP: 2.10710

Purity/Quality:

99% ^*data from raw suppliers

1-NAPHTHOYLFORMIC ACID 98.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-NAPHTHOYLFORMIC ACID

There total 10 articles about 1-NAPHTHOYLFORMIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1-naphthalenecarboxylic acid (86-55-5) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With methyl iodide; sodium sulfide; In water; isopropyl alcohol; at 20 ℃; for 20h;

DOI:10.1246/bcsj.61.4151

Reference yield:

carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1-naphthalenecarboxylic acid (86-55-5) + ethyl 1-naphthoate (3007-97-4) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With calcium hydroxide; dicobalt octacarbonyl; methyl iodide; In ethanol; water; for 20h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00388a060

Reference yield:

ethanol (64-17-5) + carbon monoxide (201230-82-2) + 1-Bromonaphthalene (90-11-9) → 1'-naphthacetophenone (941-98-0) + ethyl 1-naphthoate (3007-97-4) + 1-naphthylglycolic acid (6341-54-4) + 1-naphthylglyoxylic acid (26153-26-4)

Guidance literature:

With calcium hydroxide; dicobalt octacarbonyl; methyl iodide; In ethanol; water; for 20h; Title compound not separated from byproducts; Ambient temperature;

DOI:10.1021/jo00388a060

upstream raw materials:

ethanol

carbon monoxide

1-Bromonaphthalene

methyl iodide

Downstream raw materials:

naphth-1-yl acetic acid

2,6-dimethylphenyl 2-(naphthalen-1-yl)-2-oxoacetate

bis-[1]naphthylmethylene-hydrazine

1-Naphthylacetamide