1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone

Base Information

Chemical Name:1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone
CAS No.:274925-97-2
Molecular Formula:C15H13NO5
Molecular Weight:287.272
Hs Code.:
UNII:C2VOP33080

Synonyms:C2VOP33080;BIA 3-270;1-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone;UNII-C2VOP33080;Ethanone, 1-(4-hydroxy-3-methoxy-5-nitrophenyl)-2-phenyl-;274925-97-2;SCHEMBL7048078

Suppliers and Price of 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:287.07937252
Heavy Atom Count:21
Complexity:375

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC(=CC(=C1O)[N+](=O)[O-])C(=O)CC2=CC=CC=C2

Technology Process of 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone

There total 7 articles about 1-(4-Hydroxy-3-methoxy-5-nitrophenyl)-2-phenylethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

: 66476-02-6
1-(4-hydroxy-3-methoxyphenyl)-2-phenylethan-1-one

: 274925-97-2
BIA 3-270

Guidance literature:: With nitric acid; acetic acid;
DOI:10.1081/SCC-120002413

Reference yield:

: 2426-87-1
3-methoxy-4-(phenylmethoxy)benzaldehyde

: 274925-97-2
BIA 3-270

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / diethyl ether; tetrahydrofuran / 1 h / 20 °C

2: 91 percent / NaO-tBu; cyclohexanone / toluene / 0.5 h / Heating

3: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating

4: 71 percent / 70percent HNO₃; AcOH / 0.5 h / 20 °C

With ammonium formate; cyclohexanone; acetic acid; sodium t-butanolate; 10percent Pd/C; In tetrahydrofuran; methanol; diethyl ether; toluene; 2: Oppenauer oxidation;
DOI:10.1021/jm0109964

Reference yield:

: 274925-96-1
1-(4-benzyloxy-3-methoxyphenyl)-2-phenyl-ethanone

: 274925-97-2
BIA 3-270

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / ammonium formate / 10percent Pd/C / methanol / 0.5 h / Heating

2: 71 percent / 70percent HNO₃; AcOH / 0.5 h / 20 °C

With ammonium formate; acetic acid; 10percent Pd/C; In methanol;
DOI:10.1021/jm0109964