Eperisone

Base Information

Chemical Name:Eperisone
CAS No.:64840-90-0
Deprecated CAS:124308-54-9
Molecular Formula:C17H25NO
Molecular Weight:259.392
Hs Code.:2933399090
UNII:2M2P0551D3
DSSTox Substance ID:DTXSID5040671
Nikkaji Number:J32.876F
Wikipedia:Eperisone
Wikidata:Q426401
NCI Thesaurus Code:C83692
Pharos Ligand ID:TUD5VVMVKLW2
Metabolomics Workbench ID:152066
ChEMBL ID:CHEMBL1902981
Mol file:64840-90-0.mol

Synonyms:(4'-ethyl-2-methyl-3-piperidino)propiophenone;4-EMPP;E-0646;eperisone

Suppliers and Price of Eperisone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
1-(4-Ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one 95+%
1g
$ 772.00

Chemenu
1-(4-ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one 95%
1g
$ 729.00

American Custom Chemicals Corporation
EPERISONE 95.00%
5G
$ 1697.85

American Custom Chemicals Corporation
EPERISONE 95.00%
1G
$ 525.00

Alichem
1-(4-Ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one
1g
$ 659.40

AHH
Eperisone 98%
5g
$ 730.00

Total 49 raw suppliers

Chemical Property of Eperisone

Chemical Property:

Melting Point:170-172oC
Boiling Point:386.8 °C at 760 mmHg
Flash Point:137.4 °C
PSA：20.31000
Density:0.994 g/cm³
LogP:3.49160
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:5
Exact Mass:259.193614421
Heavy Atom Count:19
Complexity:275

Purity/Quality:

99% ^*data from raw suppliers

1-(4-Ethylphenyl)-2-methyl-3-(piperidin-1-yl)propan-1-one 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1=CC=C(C=C1)C(=O)C(C)CN2CCCCC2
Recent ClinicalTrials:Radial Extracorporeal Shock Wave Therapy for Chronic Non-specific Low Back Pain
Recent EU Clinical Trials:A pilot, prospective, randomized, open, blinded end point, phase II study of tolerability and efficacy of Eperisone in Amyotrophic Lateral Sclerosis
Recent NIPH Clinical Trials:Clinical study for companion diagnostics for type 2 diabetes (T2DM) with aberrant tRNA modification.
Description Apiresone is a central skeletal muscle relaxant with various pharmacological effects. Animal experiments suggest that eperisone hydrochloride can dose-dependently inhibit decerebral tonic (γ-rigid) and ischemic decerebral tonic (α-rigid) induced by interthalamic transection in rats, and inhibit the stimulation of the dorsal spinal cord in cats with spinal cord injury. The evoked monosynaptic and polysynaptic reflex potentials may reduce the sensitivity of muscle spindles by inhibiting the γ-neuron system.
Therapeutic Function Muscle relaxant

Technology Process of Eperisone

There total 3 articles about Eperisone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%