4-Phenylfurazanamine

Base Information

• Chemical Name: 4-Phenylfurazanamine
• CAS No.: 10349-14-1
• Molecular Formula: C8H7 N3 O
• Molecular Weight: 161.163
• Hs Code.: 2934999090
• Mol file: 10349-14-1.mol

Synonyms:Furazan,3-amino-4-phenyl- (6CI); Furazan, aminophenyl- (7CI,8CI); Furazanamine,4-phenyl-; 3-Amino-4-phenyl-1,2,5-oxadiazole; 3-Amino-4-phenylfurazan;4-Phenyl-1,2,5-oxadiazol-3-amine; 4-Phenyl-3-furazanamine

Chemical Property of 4-Phenylfurazanamine

Chemical Property:

• Vapor Pressure: 0.000481mmHg at 25°C
• Boiling Point: 313.9°Cat760mmHg
• Flash Point: 143.7°C
• PSA: 64.94000
• Density: 1.276g/cm³
• LogP: 1.90000

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-phenyl-1,2,5-oxadiazol-3-amine 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Phenylfurazanamine

There total 52 articles about 4-Phenylfurazanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

3-nitro-4-phenylfurazane (76016-68-7) → 4-phenyl-furazan-3-ylamine (10349-14-1)

Guidance literature:

With ammonia; In benzene; at 125 ℃; for 3h; under 11400 Torr;

DOI:10.1023/A:1020931511013

Reference yield: 81.0%

3-nitro-4-phenyl-1,2,5-oxadiazole 2-oxide (76016-69-8) → 4-phenyl-furazan-3-ylamine (10349-14-1)

Guidance literature:

With hydrogenchloride; tin(ll) chloride; at 20 ℃; for 1h; chemoselective reaction;

DOI:10.1055/s-0037-1611056

Reference yield: 75.0%

methyl 3-oxo-3-phenylpropionate (614-27-7) → 4-phenyl-furazan-3-ylamine (10349-14-1)

Guidance literature:

Multistep reaction;

DOI:10.1007/s11172-005-0359-4

upstream raw materials:

3-amino-4-phenylfuroxane

4-amino-3-phenylfuroxane

ethanol

1-methyl-4-nitrosobenzene

Downstream raw materials:

3-(Acetylamino)-4-phenylfurazan

N-(phenyl-furazan-3-yl)-diacetamide

N-(4-phenyl-1,2,5-oxadiazol-3-yl)benzamide

Phenanthridin-6-yl-(4-phenyl-furazan-3-yl)-amine

Refernces

• 1、 Dolensky, Johanna,Hermann, Theresa,Hochegger, Patrick,Kaiser, Marcel,M?ser, Pascal,Saf, Robert,Seebacher, Werner,Weis, Robert. "New acyl derivatives of 3-aminofurazanes and their antiplasmodial activities". . . Retrieved 2021/05/24.
• 2、 Zhilin, Egor S.,Bystrov, Dmitry M.,Ananyev, Ivan V.,Fershtat, Leonid L.,Makhova, Nina N.. "Straightforward Access to the Nitric Oxide Donor Azasydnone Scaffold by Cascade Reactions of Amines". supporting information. p. 14284 - 14289. Retrieved 2019/11/11.