2-(4-Iodo-phenoxy)-ethanol

Base Information

• Chemical Name: 2-(4-Iodo-phenoxy)-ethanol
• CAS No.: 29639-77-8
• Molecular Formula: C8H9IO2
• Molecular Weight: 264.063
• Hs Code.: 2909499000
• Mol file: 29639-77-8.mol

Synonyms:2-(4-Iodo-phenoxy)-ethanol;2-(4-iodophenoxy)ethanol;4-(2-hydroxyethoxy)phenyl iodide;4-(2-hydroxyethoxy)-1-iodobenzene;

Chemical Property of 2-(4-Iodo-phenoxy)-ethanol

Chemical Property:

• PSA: 29.46000
• LogP: 1.66230

Purity/Quality:

99% ^*data from raw suppliers

2-(4-Iodophenoxy)ethanol 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Iodo-phenoxy)-ethanol

There total 9 articles about 2-(4-Iodo-phenoxy)-ethanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

p-Iodophenol (540-38-5) + 2-chloro-ethanol (107-07-3) → 2-(4-iodophenoxy)ethanol (29639-77-8)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 18h;

Reference yield: 92.0%

2-Phenoxyethanol (122-99-6,56257-90-0,9004-78-8) → 2-(4-iodophenoxy)ethanol (29639-77-8) + 2-(2,4-Diiodo-phenoxy)-ethanol

Guidance literature:

With [bis(acetoxy)iodo]benzene; iodine; In ethyl acetate; for 4h; Yields of byproduct given; Ambient temperature;

DOI:10.1055/s-1998-1713

Reference yield: 81.0%

2-Phenoxyethanol (122-99-6,56257-90-0,9004-78-8) → 2-(4-iodophenoxy)ethanol (29639-77-8)

Guidance literature:

With Iron(III) nitrate nonahydrate; carbon dioxide; iodine; oxygen; In ethylene glycol; at 100 ℃; for 10h; under 5250.53 - 9000.9 Torr; regioselective reaction; Autoclave; Green chemistry;

DOI:10.1039/c4cy00721b

upstream raw materials:

2-Phenoxyethanol

p-Iodophenol

2-bromoethanol

2-chloro-ethanol

Downstream raw materials:

tert-Butyl-[2-(4-iodo-phenoxy)-ethoxy]-diphenyl-silane

2-(4-(4-(4-(dimethylamino)phenyl)-1H-1,2,3-triazol-1-yl)phenoxy)ethanol

2-{4-[5-(4-chloro-phenyl)-pyridin-2-ylethynyl]-phenoxy}-ethanol

2-(4-trimethylsilanylethynyl-phenoxy)-ethanol