Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-

Base Information

Chemical Name:Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-
CAS No.:296766-47-7
Molecular Formula:C15H21NO5
Molecular Weight:295.335
Hs Code.:
DSSTox Substance ID:DTXSID80443532
Nikkaji Number:J1.354.051I,J1.354.052G
Mol file:296766-47-7.mol

Synonyms:Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-;296766-47-7;DTXSID80443532;N-[2alpha-(2,2-Dimethoxyethyl)-1,3-dioxane-5alpha-yl]benzamide;N-[2alpha-(2,2-Dimethoxyethyl)-1,3-dioxane-5beta-yl]benzamide

Suppliers and Price of Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-

Chemical Property:

Melting Point:140-142 °C
Boiling Point:461.0±45.0 °C(Predicted)
PSA：69.51000
Density:1.18±0.1 g/cm3(Predicted)
LogP:1.74170
XLogP3:1.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:6
Exact Mass:295.14197277
Heavy Atom Count:21
Complexity:307

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(CC1OCC(CO1)NC(=O)C2=CC=CC=C2)OC

Technology Process of Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]-

There total 4 articles about Benzamide, N-[cis-2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 106084-38-2
[cis-2-(2',2'-dimethoxyethyl)-1,3-dioxan-5-yl]amine

: 98-88-4
benzoyl chloride

: 296766-47-7
N-[cis-2-(2',2'-dimethoxyethyl)-1,3-dioxan-5-yl]benzoylamine

Guidance literature:: With triethylamine; In chloroform; at 20 ℃; for 3h;
DOI:10.1016/j.bmc.2005.09.068

Reference yield: 43.0%

: 102-52-3
malonaldehydebis(dimethylacetal)

: 138625-63-5
N-[2-hydroxy-1-(hydroxymethyl)ethyl]benzamide

: (trans)-N-[2-(2,2-dimethoxyethyl)-1,3-dioxan-5-yl]benzamide

: 296766-47-7
N-[cis-2-(2',2'-dimethoxyethyl)-1,3-dioxan-5-yl]benzoylamine

: 296766-49-9
N,N'-methylenebis[(cis)/(trans)-1,3-dioxan-2,5-diyl]bisbenzamide

: N,N'-methylenebis[(cis)/(cis)-1,3-dioxan-2,5-diyl]bisbenzamide

Guidance literature:: With hydrogenchloride; In chloroform; at 40 ℃; for 12h;
DOI:10.1002/1099-0690(200007)2000:14<2669::aid-ejoc2669>3.3.co;2-q

Reference yield:

: 879559-63-4
cis-2-(2,2-dimethoxyethyl)-5-trifluoroacetylamino-1,3-dioxacyclohexane

: 296766-47-7
N-[cis-2-(2',2'-dimethoxyethyl)-1,3-dioxan-5-yl]benzoylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / NaOH / H₂O; ethanol / 3 h / 20 °C

2: 98 percent / triethylamine / CHCl₃ / 3 h / 20 °C

With sodium hydroxide; triethylamine; In ethanol; chloroform; water;
DOI:10.1016/j.bmc.2005.09.068