5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid

Base Information

Chemical Name:5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid
CAS No.:137292-30-9
Molecular Formula:C23H31 N3 O3
Molecular Weight:397.517
Hs Code.:
Nikkaji Number:J626.424G
Pharos Ligand ID:M9YRLLXGCJWY
ChEMBL ID:CHEMBL120181
Mol file:137292-30-9.mol

Synonyms:5-(1-cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid;FCE 27262;FCE-27262

Suppliers and Price of 5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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Total 1 raw suppliers

Chemical Property of 5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid

Chemical Property:

Vapor Pressure:3.29E-16mmHg at 25°C
Boiling Point:619.5°Cat760mmHg
Flash Point:328.5°C
PSA：76.71000
Density:1.17g/cm³
LogP:4.87470
XLogP3:4.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:397.23654186
Heavy Atom Count:29
Complexity:514

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CCC(CC1)C(=NOCCCCC(=O)O)C(CC2=CC=CC=C2)N3C=CN=C3
Isomeric SMILES:C1CCC(CC1)/C(=N\OCCCCC(=O)O)/C(CC2=CC=CC=C2)N3C=CN=C3

Technology Process of 5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid

There total 4 articles about 5-(1-Cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene)aminooxypentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 142223-42-5
ethyl (+/-)-(E+Z)-5-<<<1-cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropylidene>amino>oxy>pentanoate

: 5-[1-Cyclohexyl-2-imidazol-1-yl-3-phenyl-prop-(Z)-ylideneaminooxy]-pentanoic acid

: 137292-30-9
(+/-)-(E)-5-[2-benzyl-2-(imidazol-1-yl)-1-cyclohexylethylidene]aminooxypentanoic acid

Guidance literature:: With sodium hydroxide; In ethanol; for 4h; Ambient temperature;
DOI:10.1021/jm00047a016

Reference yield:

: 14660-52-7
ethyl 5-bromovalerate

: 137292-30-9
(+/-)-(E)-5-[2-benzyl-2-(imidazol-1-yl)-1-cyclohexylethylidene]aminooxypentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 2.) DMF, RT, 2 h

2: 60 percent / 1N aq. NaOH / ethanol / 4 h / Ambient temperature

With sodium hydroxide; sodium hydride; In ethanol;
DOI:10.1021/jm00047a016

Reference yield:

: (+/-)-(E+Z)-1-cyclohexyl-2-(1H-imidazol-1-yl)-3-phenylpropan-1-one oxime

: 137292-30-9
(+/-)-(E)-5-[2-benzyl-2-(imidazol-1-yl)-1-cyclohexylethylidene]aminooxypentanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) NaH / 1.) DMF, RT, 2.) DMF, RT, 2 h

2: 60 percent / 1N aq. NaOH / ethanol / 4 h / Ambient temperature

With sodium hydroxide; sodium hydride; In ethanol;
DOI:10.1021/jm00047a016