1-(Thiophen-3-yl)butane-1,3-dione

Base Information

• Chemical Name: 1-(Thiophen-3-yl)butane-1,3-dione
• CAS No.: 3115-63-7
• Molecular Formula: C8H8O2S
• Molecular Weight: 0.00000
• Mol file: 3115-63-7.mol

Synonyms:

Chemical Property of 1-(Thiophen-3-yl)butane-1,3-dione

Chemical Property:

• PSA: 0.00000
• LogP: 0.00000
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

95% ^*data from raw suppliers

1-Thiophen-3-yl-butane-1,3-dione 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(Thiophen-3-yl)butane-1,3-dione

There total 1 articles about 1-(Thiophen-3-yl)butane-1,3-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

3-thienyl iodide (10486-61-0) + carbon monoxide (201230-82-2) + acetone (67-64-1) → 1-(thiophen-3-yl)butane-1,3-dione (3115-63-7)

Guidance literature:

With bis[chloro(1,2,3-trihapto-allylbenzene)palladium(II)]; di-(1-adamantyl)-n-butylphosphine; caesium carbonate; at 60 ℃; for 36h; under 2250.23 Torr; Glovebox; Inert atmosphere; Autoclave;

DOI:10.1002/chem.201302590

Reference yield: 60.0%

1-(thiophen-3-yl)butane-1,3-dione (3115-63-7) + sodium 4-methylbenzenesulfinate (824-79-3) + toluene-4-sulfonic acid hydrazide (1576-35-8) → 3-methyl-5-(thiophen-3-yl)-1,4-ditosyl-1H-pyrazole

Guidance literature:

With potassium hydrogenphosphate trihydrate; iodine; In acetonitrile; at 20 ℃; for 22h; Schlenk technique; Sealed tube;

DOI:10.1021/acs.joc.1c00171

upstream raw materials:

3-thienyl iodide

carbon monoxide

acetone

Refernces