Pharmakon1600-01500673

Base Information

• Chemical Name: Pharmakon1600-01500673
• CAS No.: 25717-80-0
• Molecular Formula: C9H14N4O4
• Molecular Weight: 242.235
• Hs Code.: 29349990
• NSC Number: 757398
• Mol file: 25717-80-0.mol

Synonyms:Pharmakon1600-01500673;NSC757398;NCGC00179510-01;BRD-K35531059-001-02-4

Chemical Property of Pharmakon1600-01500673

Chemical Property:

• Appearance/Colour: colorless or white crystalline powder
• Melting Point: 140-141 °C
• Refractive Index: 1.6300 (estimate)
• Boiling Point: 385.05°C (rough estimate)
• PKA: pK (100°) 3.0 ± 0.1
• PSA: 82.09000
• Density: 1.3186 (rough estimate)
• LogP: -0.43350
• Storage Temp.: 2-8°C
• Solubility.: Sparingly soluble in water, soluble in anhydrous ethanol and in methylene chloride.
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 4
• Exact Mass: 242.10150494
• Heavy Atom Count: 17
• Complexity: 270

Purity/Quality:

98.5% ^*data from raw suppliers

Molsidomine ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 22
• Safety Statements: 36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CCOC(=NC1=C[N+](=NO1)N2CCOCC2)[O-]
• Isomeric SMILES: CCO/C(=N\C1=C[N+](=NO1)N2CCOCC2)/[O-]
• Uses: Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitr ic oxide donor. Molsidomine is an antianginal agent. Molsidomine is an effective therapeutic agents in the treatment of angina pectoris. Molsidomine is a sydnonimine derivative that acts as a heterocyclic direct nitric oxide donor.
• Therapeutic Function: Coronary vasodilator

Technology Process of Pharmakon1600-01500673

There total 3 articles about Pharmakon1600-01500673 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-lithiomolsidomine → molsidomine (25717-80-0)

Guidance literature:

With water;

DOI:10.1016/j.tet.2017.07.032

Reference yield:

→ molsidomine (25717-80-0) + Sucrose (57-50-1)

Guidance literature:

Reference yield:

chloroformic acid ethyl ester (541-41-3) + Linsidomine hydrochloride (16142-27-1) → molsidomine (25717-80-0)

Guidance literature:

With sodium hydrogencarbonate;

upstream raw materials:

chloroformic acid ethyl ester

Linsidomine hydrochloride

Downstream raw materials:

morpholine

Refernces

• 1、 -. "Spherical granules having core and their production". . . Retrieved 2008/06/13.