1,1'-Biphenyl, 3-(methylthio)-

Base Information

• Chemical Name: 1,1'-Biphenyl, 3-(methylthio)-
• CAS No.: 31477-46-0
• Molecular Formula: C13H12S
• Molecular Weight: 200.304
• DSSTox Substance ID: DTXSID10467842
• Nikkaji Number: J2.464.133C
• Wikidata: Q82294916
• Mol file: 31477-46-0.mol

Synonyms:31477-46-0;1,1'-Biphenyl, 3-(methylthio)-;[1,1'-Biphenyl]-3-yl(methyl)sulfane;1-methylsulfanyl-3-phenylbenzene;1-(methylsulfanyl)-3-phenylbenzene;3-(Methylthio)biphenyl;SCHEMBL3480820;DTXSID10467842

Chemical Property of 1,1'-Biphenyl, 3-(methylthio)-

Chemical Property:

• PSA: 25.30000
• LogP: 4.07550
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 200.06597156
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

99% ^*data from raw suppliers

1-(METHYLSULFANYL)-3-PHENYLBENZENE ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CSC1=CC=CC(=C1)C2=CC=CC=C2

Technology Process of 1,1'-Biphenyl, 3-(methylthio)-

There total 4 articles about 1,1'-Biphenyl, 3-(methylthio)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

bromobenzene (108-86-1,52753-63-6) + 3-methylthiophenylboronic acid (128312-11-8) → methyl-phenyl-thioether (100-68-5) + 3-methylsulfanylbiphenyl (31477-46-0) + 3,3'-di(methylthio)biphenyl (10075-91-9)

Guidance literature:

With potassium carbonate; dihydrogendichlorobis(di-tert-butylphosphinito-κP)palladate; In 1,4-dioxane; for 5h; Further Variations:; Solvents; Product distribution; Heating;

DOI:10.1080/00397910601131049

Reference yield: 92.0%

2-(4-methylthiophenyl)-4-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-henicosafluorodecyl)-[1,3,2]dioxaborolane (884844-91-1) + iodobenzene (591-50-4) → 3-methylsulfanylbiphenyl (31477-46-0)

Guidance literature:

With potassium phosphate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In 1,4-dioxane; for 20h; Heating;

DOI:10.1016/j.jfluchem.2004.12.014

Reference yield: 45.0%

1,1-Bis-methylsulfanyl-3-phenyl-hexa-1,5-dien-3-ol → 3-methylsulfanylbiphenyl (31477-46-0)

Guidance literature:

With boron trifluoride diethyl etherate; In benzene; for 0.5h; Heating;

DOI:10.1016/S0040-4039(01)91128-1

upstream raw materials:

3-biphenyl amine

dimethyl sulfate

2-(4-methylthiophenyl)-4-(2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-henicosafluorodecyl)-[1,3,2]dioxaborolane

iodobenzene

Downstream raw materials:

biphenyl