N-(Cinnamylidene)-M-toluidine

Base Information

• Chemical Name: N-(Cinnamylidene)-M-toluidine
• CAS No.: 33798-39-9
• Molecular Formula: C₁₆H₁₅N
• Molecular Weight: 221.302
• European Community (EC) Number: 666-960-3
• Nikkaji Number: J1.397.255I,J736.275G
• Mol file: 33798-39-9.mol

Synonyms:N-trans-Cinnamylidene-m-toluidine;N-(CINNAMYLIDENE)-M-TOLUIDINE;AKOS024334929;N-(3-Phenylallylidene)-3-methylaniline

Chemical Property of N-(Cinnamylidene)-M-toluidine

Chemical Property:

• XLogP3: 4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 221.120449483
• Heavy Atom Count: 17
• Complexity: 261

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)N=CC=CC2=CC=CC=C2
• Isomeric SMILES: CC1=CC(=CC=C1)N=C/C=C/C2=CC=CC=C2

Technology Process of N-(Cinnamylidene)-M-toluidine

There total 4 articles about N-(Cinnamylidene)-M-toluidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-methyl-3-nitrobenzene (99-08-1) + 3-phenyl-propenal (104-55-2) → 3-methyl-N-(3-phenylallylidene)aniline (135088-55-0,33798-39-9)

Guidance literature:

With methanol; 3%Au-3%Pd/Al2O3; water; at 134.84 ℃; under 15001.5 Torr; Inert atmosphere; Autoclave;

DOI:10.1039/c0cc00531b

Reference yield:

3-phenyl-propenal (104-55-2) + 1-amino-3-methylbenzene (108-44-1) → 3-methyl-N-(3-phenylallylidene)aniline (135088-55-0,33798-39-9)

Guidance literature:

Reference yield:

benzaldehyde (100-52-7) → 3-methyl-N-(3-phenylallylidene)aniline (135088-55-0,33798-39-9)

Guidance literature:

Multi-step reaction with 2 steps

1: toluene / 17 h / 85 °C

2: magnesium sulfate / dichloromethane / 20 °C

With magnesium sulfate; In dichloromethane; toluene; 1: |Wittig Olefination;

DOI:10.1002/chem.201800958

upstream raw materials:

3-phenyl-propenal

1-amino-3-methylbenzene

1-methyl-3-nitrobenzene

benzaldehyde

Downstream raw materials:

Phenyl-m-tolyl-(2,3,3-triphenyl-propyl)-amine