1-Propanone, 1,2-bis(4-methoxyphenyl)-

Base Information

• Chemical Name: 1-Propanone, 1,2-bis(4-methoxyphenyl)-
• CAS No.: 35258-41-4
• Molecular Formula: C17H18O3
• Molecular Weight: 270.328
• DSSTox Substance ID: DTXSID80456309
• Nikkaji Number: J3.054.421H
• Mol file: 35258-41-4.mol

Synonyms:1-Propanone, 1,2-bis(4-methoxyphenyl)-;35258-41-4;SCHEMBL16162246;DTXSID80456309;GANRUTSEZQVUIO-UHFFFAOYSA-N;1,2-Bis(4-methoxyphenyl)-1-propanone;1,2-Di(4'-methoxyphenyl)-1-propanone

Chemical Property of 1-Propanone, 1,2-bis(4-methoxyphenyl)-

Chemical Property:

• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 270.125594432
• Heavy Atom Count: 20
• Complexity: 299

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C1=CC=C(C=C1)OC)C(=O)C2=CC=C(C=C2)OC

Technology Process of 1-Propanone, 1,2-bis(4-methoxyphenyl)-

There total 10 articles about 1-Propanone, 1,2-bis(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

4-methoxy-N,N,N-trimethylbenzenaminium trifluoromethanesulfonate + 4-Methoxypropiophenone (121-97-1) → 1,2-bis-(4-methoxy-phenyl)-propan-1-one (35258-41-4)

Guidance literature:

With bis(1,5-cyclooctadiene)nickel ⁽⁰⁾; 1,3-bis(2,6-diisopropylphenyl)imidazolium chloride; lithium tert-butoxide; In tetrahydrofuran; at 80 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1039/c6ob01299j

Reference yield: 68.0%

1,4-di(4-methoxyphenyl)ethanone (120-44-5) + methyl iodide (74-88-4) → 1,2-bis-(4-methoxy-phenyl)-propan-1-one (35258-41-4)

Guidance literature:

With potassium tert-butylate; In diethyl ether; for 6h; Heating;

DOI:10.1021/jm0210562

Reference yield: 55.0%

1,4-di(4-methoxyphenyl)ethanone (120-44-5) + methyl iodide (74-88-4) → 1,2-bis-(4-methoxy-phenyl)-propan-1-one (35258-41-4) + 1,2-bis-(4-methoxy-phenyl)-2-methyl-propan-1-one (96047-37-9)

Guidance literature:

With 18-crown-6 ether; potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1016/j.ejmech.2009.02.006

upstream raw materials:

1,1-bis(4-methoxyphenyl)propene

1,4-di(4-methoxyphenyl)ethanone

methyl iodide

(E)-1-methoxy-1,2-bis(p-methoxyphenyl)propene

Downstream raw materials:

1,2-bis-(4-hydroxy-phenyl)-propan-1-one

1, 2-bis(4-methoxyphenyl)prop-2-en-1-one

1-(4-methoxyphenyl)ethanone

1,2-bis-(4-methoxy-phenyl)-2-methyl-propan-1-one