diethyl ethyl[2-(2-nitrophenyl)ethyl]propanedioate

Base Information

• Chemical Name: diethyl ethyl[2-(2-nitrophenyl)ethyl]propanedioate
• CAS No.: 5345-28-8
• Molecular Formula: C₁₇H₂₃NO₆
• Molecular Weight: 337.373
• Mol file: 5345-28-8.mol

Synonyms:NSC 3020

Chemical Property of diethyl ethyl[2-(2-nitrophenyl)ethyl]propanedioate

Chemical Property:

• Vapor Pressure: 4.94E-08mmHg at 25°C
• Boiling Point: 442.6°Cat760mmHg
• Flash Point: 164.3°C
• Density: 1.164g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of diethyl ethyl[2-(2-nitrophenyl)ethyl]propanedioate

There total 2 articles about diethyl ethyl[2-(2-nitrophenyl)ethyl]propanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2-bromoethyl)-2-nitrobenzene (16793-89-8) → ethyl-(2-nitro-phenethyl)-malonic acid diethyl ester (5345-28-8)

Guidance literature:

Multi-step reaction with 2 steps

1: aqueous tris-<2-hydroxy-ethyl>-amine

2: ethanolic sodium ethylate

With triethanolamine; sodium ethanolate;

DOI:10.1021/ja01652a090

Reference yield:

2-nitrostyrene (579-71-5) + ethyl diethyl malonate (133-13-1) → ethyl-(2-nitro-phenethyl)-malonic acid diethyl ester (5345-28-8)

Guidance literature:

With sodium ethanolate;

DOI:10.1021/ja01652a090

upstream raw materials:

2-nitrostyrene

ethyl diethyl malonate

(2-bromoethyl)-2-nitrobenzene