1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl-

Base Information

• Chemical Name: 1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl-
• CAS No.: 365214-51-3
• Molecular Formula: C18H11Cl2NO2
• Molecular Weight: 344.197
• DSSTox Substance ID: DTXSID80478369
• Nikkaji Number: J2.309.152F
• Wikidata: Q82311716
• Mol file: 365214-51-3.mol

Synonyms:1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl-;365214-51-3;DTXSID80478369

Chemical Property of 1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl-

Chemical Property:

• XLogP3: 5.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 343.0166840
• Heavy Atom Count: 23
• Complexity: 404

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C2=C(NC(=C2C3=CC=CC=C3)C(=O)Cl)C(=O)Cl

Technology Process of 1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl-

There total 1 articles about 1H-Pyrrole-2,5-dicarbonyl dichloride, 3,4-diphenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,4-diphenyl-1H-pyrrole-2,5-dicarboxylic acid (1632-49-1) → 3,4-diphenylpyrrole-2,5-dicarboxylic acid chloride (365214-51-3)

Guidance literature:

With thionyl chloride; Heating;

DOI:10.1016/S0040-4039(01)00896-6

Reference yield: 70.0%

ethylenediamine (107-15-3,85404-18-8) + 3,4-diphenylpyrrole-2,5-dicarboxylic acid chloride (365214-51-3) → 3,4-diphenyl-1H-pyrrole-2,5-dicarboxylic acid bis-[(2-amino-ethyl)-amide]

Guidance literature:

With dmap; In dichloromethane;

DOI:10.1039/b204295a

Reference yield: 31.0%

aminoferrocene (1273-82-1) + 3,4-diphenylpyrrole-2,5-dicarboxylic acid chloride (365214-51-3) → 3,4-diphenyl-1H-pyrrole-2,5-dicarboxylic acid diferrocenylmethyl-amide (475148-10-8)

Guidance literature:

With Et₃N; 4-N,N-dimethylaminopyridine; In dichloromethane; stirring soln. of diphenyl-pyrrole-dicarbonyl dichloride in dry CH2Cl2 under N2, addn. of Et3N, catalytic amt. of dimethylaminopyridine, and slight excess of Fe-compd., stirring under N2 overnight; solvent was removed in vac., residue was redissolved in MeCN, ppt. was sepd., washed 3 times with MeCN and H2O, resp., dried in high vac. for 2 h, chromy. (silica/ CH2Cl2-2% MeOH);

DOI:10.1039/b202989h

upstream raw materials:

3,4-diphenyl-1H-pyrrole-2,5-dicarboxylic acid

Downstream raw materials:

N₂,N₅-dibutyl-3,4-diphenyl-1H-pyrrole-2,5-dicarboxamide

N₂,N₅,3,4-tetraphenyl-1H-pyrrole-2,5-dicarboxamide

N,N'-bis(3,5-dinitrophenyl)-3,4-diphenyl-1H-pyrrole-2,5-dicarboxamide

3,4-diphenyl-1H-pyrrole-2,5-dicarboxylic acid bisferrocenylamide