Benzeneacetaldehyde, a-(phenylsulfonyl)-

Base Information

• Chemical Name: Benzeneacetaldehyde, a-(phenylsulfonyl)-
• CAS No.: 38509-32-9
• Molecular Formula: C14H12O3S
• Molecular Weight: 260.313
• Mol file: 38509-32-9.mol

Synonyms:

Chemical Property of Benzeneacetaldehyde, a-(phenylsulfonyl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzeneacetaldehyde, a-(phenylsulfonyl)-

There total 12 articles about Benzeneacetaldehyde, a-(phenylsulfonyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

rel-2R,3R-2-phenyl-3-(phenylsulfonyl)oxirane (26995-39-1,61937-46-0,111832-38-3,117841-06-2) → α-Phenylsulfonyl-phenylacetaldehyd (38509-32-9)

Guidance literature:

rel-2R,3R-2-phenyl-3-(phenylsulfonyl)oxirane; With boron trifluoride diethyl etherate; In dichloromethane; at -20 ℃; for 0.0833333h;

With water; sodium hydrogencarbonate; In dichloromethane;

DOI:10.1021/ol100862s

Reference yield: 26.0%

2-phenyl-1-(phenylsulfonyl)-1,2-epoxyethane (61937-46-0) → α-Phenylsulfonyl-phenylacetaldehyd (38509-32-9)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; at 0 ℃; for 0.166667h;

DOI:10.1021/ja962949k

Reference yield:

chloromethyl phenyl sulfone (7205-98-3) → α-Phenylsulfonyl-phenylacetaldehyd (38509-32-9)

Guidance literature:

Multi-step reaction with 2 steps

1: 67 percent / aq. NaOH, benzyltriethylammonium chloride / acetonitrile / 1.5 h / 0 °C

2: 26 percent / BF₃*Et₂O / CH₂Cl₂ / 0.17 h / 0 °C

With sodium hydroxide; boron trifluoride diethyl etherate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; acetonitrile;

DOI:10.1021/ja962949k

upstream raw materials:

2-phenyl-1-(phenylsulfonyl)-1,2-epoxyethane

(Z)-β-isopropoxy-α-(phenylsulfonyl)styrene

2-phenylethynyl methyl selenide

sodium benzenesulfonate

Downstream raw materials:

phenyl(phenylsulfonyl)diazomethane

phenyl phenylsulfonyl ketone

diphenylsulfene

phenyl(phenylsulfonyl)carbene