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41248-23-1

Basic Information
CAS No.: 41248-23-1
Name: ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE
Article Data: 9
Molecular Structure:
Molecular Structure of 41248-23-1 (ETHYL 1-HYDROXYCYCLOPENTANE-CARBOXYLATE)
Formula: C8H14O3
Molecular Weight: 158.197
Synonyms: ethyl 1-hydroxycyclopentane-1-carboxylate;
Density: 1.144
Boiling Point: 206oC
Flash Point: 77oC
PSA: 46.53000
LogP: 0.71050
Synthetic route
16841-19-3

1-hydroxy-cyclopentanecarboxylic acid

64-17-5

ethanol

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
With sulfuric acid at 20℃; for 72h;95%
With sulfuric acid90%
With sulfuric acid
64-17-5

ethanol

5117-85-1

1-hydroxycyclopentanecarbonitrile

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
With hydrogenchloride In water at -10 - 25℃; for 14h;90%
5117-85-1

1-hydroxycyclopentanecarbonitrile

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: conc. HCl / Heating
2: HCl / Heating
View Scheme
Multi-step reaction with 2 steps
1: aq. HCl
2: p-TsOH
View Scheme
Multi-step reaction with 2 steps
1: hydrogenchloride; acetic acid / 10 h
2: sulfuric acid
View Scheme
120-92-3

cyclopentanone

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. H2SO4 / 20 °C
2: conc. HCl / Heating
3: HCl / Heating
View Scheme
120-92-3

cyclopentanone

(CH3)2N-(CH=CH)2-CH(Y)N(CH3)2, Y=N(CH3)2 and OCH3

(CH3)2N-(CH=CH)2-CH(Y)N(CH3)2, Y=N(CH3)2 and OCH3

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: aq. HCl
2: p-TsOH
View Scheme
96-41-3

Cyclopentanol

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: sodium metabisulfite
2: hydrogenchloride; acetic acid / 10 h
3: sulfuric acid
View Scheme
1031387-31-1

(5-bromo-2-methylphenyl)acetyl chloride

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

1031386-56-7

C17H21BrO4

Conditions
ConditionsYield
at 120℃; for 6h;99%
1210776-68-3

2-chloro-4-methyl-6-methoxy-phenylacetyl chloride

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

866386-36-9

C18H23ClO5

Conditions
ConditionsYield
at 120 - 140℃;87%
4408-60-0

2-mesitylacetic acid

41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

148476-30-6

3-(2,4,6-trimethylphenyl)-2-oxo-1-oxaspiro[4,4]indole-3-en-4-ol

Conditions
ConditionsYield
Stage #1: 2-mesitylacetic acid; hydroxycyclopentanecarboxylic acid ethyl ester With trichlorophosphate In toluene at 20℃;
Stage #2: With sodium hydroxide In toluene for 8h; Reflux;
85%
41248-23-1

hydroxycyclopentanecarboxylic acid ethyl ester

3019-71-4

Trichloroacetyl isocyanate

67852-27-1

cyclopentanespiro-5'-oxazolidine-2',4'-dione

Conditions
ConditionsYield
Stage #1: hydroxycyclopentanecarboxylic acid ethyl ester; Trichloroacetyl isocyanate In dichloromethane at 0 - 20℃;
Stage #2: With triethylamine In ethanol Reflux;
77%
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