4-nitro-N-(pyridin-2-yl)benzenesulfonamide

Base Information

• Chemical Name: 4-nitro-N-(pyridin-2-yl)benzenesulfonamide
• CAS No.: 1028-11-1
• Molecular Formula: C11H9 N3 O4 S
• Molecular Weight: 279.276
• Hs Code.: 2935009090
• Nikkaji Number: J590.815I
• ChEMBL ID: CHEMBL594811
• Mol file: 1028-11-1.mol

Synonyms:4-nitro-N-(pyridin-2-yl)benzenesulfonamide;4-nitro-N-pyridin-2-ylbenzenesulfonamide;4-Nitro-N-pyridin-2-yl-benzenesulfonamide;Oprea1_380332;Oprea1_574292;MLS001211291;CHEMBL594811;SCHEMBL2407197;HMS2840J06;STK416448;AKOS000668540;SMR000504860;N-(2-Pyridinyl)-4-nitrobenzenesulfonamide;SR-01000788618;SR-01000788618-3;4-Nitro-N-[(2Z)-pyridinylidene]benzenesulfonamide #;Z45654191;N-(1,2-Dihydro-2-pyridylidene)-4-nitrobenzenesulfonamide

Chemical Property of 4-nitro-N-(pyridin-2-yl)benzenesulfonamide

Chemical Property:

• Vapor Pressure: 2.48E-09mmHg at 25°C
• Boiling Point: 478.9°Cat760mmHg
• Flash Point: 243.4°C
• PSA: 104.47000
• Density: 1.496g/cm³
• LogP: 3.07260
• XLogP3: 0.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 3
• Exact Mass: 279.03137695
• Heavy Atom Count: 19
• Complexity: 407

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Nitro-N-pyridin-2-ylbenzenesulfonamide 95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=NC(=C1)NS(=O)(=O)C2=CC=C(C=C2)[N+](=O)[O-]

Technology Process of 4-nitro-N-(pyridin-2-yl)benzenesulfonamide

There total 9 articles about 4-nitro-N-(pyridin-2-yl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2-aminopyridine (504-29-0) + di(p-nitrophenyl) disulfide (100-32-3) → 4-nitro-N-(pyridin-2-yl)benzenesulfonamide (1028-11-1)

Guidance literature:

With dihydrogen peroxide; copper diacetate; zirconium(IV) chloride; In acetonitrile; at 60 ℃; for 4h; Reagent/catalyst; Solvent;

Reference yield: 63.0%

2-aminopyridine (504-29-0) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → 4-nitro-N-(pyridin-2-yl)benzenesulfonamide (1028-11-1)

Guidance literature:

With pyridine; at 0 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.bmc.2009.09.030

Reference yield:

4-nitro-benzenesulfenic acid-[2]pyridylamide (35069-81-9) → 4-nitro-N-(pyridin-2-yl)benzenesulfonamide (1028-11-1)

Guidance literature:

With dihydrogen peroxide; acetic acid;

upstream raw materials:

2-aminopyridine

4-nitro-benzenesulfinic acid

4-Nitrobenzenesulfonyl chloride

4-nitro-benzenesulfenic acid-[2]pyridylamide

Downstream raw materials:

(E)-4-((4-hydroxy-3,5-dimethylphenyl)diazenyl)-N-(pyridin-2-yl)-benzenesulfonamide