3-Fluoro-6-methoxyquinoline

Base Information

Chemical Name:3-Fluoro-6-methoxyquinoline
CAS No.:426842-85-5
Molecular Formula:C10H8FNO
Molecular Weight:177.17500
Hs Code.:2933499090
European Community (EC) Number:696-509-6
DSSTox Substance ID:DTXSID90461883
Wikidata:Q82286331
Mol file:426842-85-5.mol

Synonyms:3-fluoro-6-methoxyquinoline

Suppliers and Price of 3-Fluoro-6-methoxyquinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
3-Fluoro-6-methoxyquinoline >97%
500mg
$ 908.00

Crysdot
3-Fluoro-6-methoxyquinoline 95+%
1g
$ 606.00

Chemenu
3-Fluoro-6-methoxyquinoline 95%
1g
$ 567.00

Apolloscientific
3-Fluoro-6-methoxyquinoline
500mg
$ 356.00

American Custom Chemicals Corporation
3-FLUORO-6-METHOXYQUINOLINE 95.00%
5MG
$ 505.45

Ambeed
3-Fluoro-6-methoxyquinoline 95+%
5g
$ 662.00

Ambeed
3-Fluoro-6-methoxyquinoline 95+%
1g
$ 185.00

Ambeed
3-Fluoro-6-methoxyquinoline 95+%
250mg
$ 74.00

Ambeed
3-Fluoro-6-methoxyquinoline 95+%
100mg
$ 50.00

AK Scientific
3-Fluoro-6-methoxyquinoline
500mg
$ 1003.00

Total 9 raw suppliers

Chemical Property of 3-Fluoro-6-methoxyquinoline

Chemical Property:

Boiling Point:284.0±20.0 °C(Predicted)
PKA:2.34±0.14(Predicted)
PSA：22.12000
Density:1?+-.0.06 g/cm3(Predicted)
LogP:2.38250
XLogP3:2.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:177.058992041
Heavy Atom Count:13
Complexity:176

Purity/Quality:

97% ^*data from raw suppliers

3-Fluoro-6-methoxyquinoline >97% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=CC(=CN=C2C=C1)F

Technology Process of 3-Fluoro-6-methoxyquinoline

There total 24 articles about 3-Fluoro-6-methoxyquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 4-chloro-3-fluoro-6-methoxyquinoline

: 426842-85-5
4-chloro-3-fluoro-6-methoxyquinoline

Guidance literature:: With formic acid; 20% palladium hydroxide-activated charcoal; triethylamine; In Isopropyl acetate; at 20 - 25 ℃; for 17h; Inert atmosphere;
DOI:10.1021/acs.oprd.1c00414

Reference yield: 93.0%

: 1086533-18-7
2,4-dichloro-3-fluoro-6-methoxyquinoline

: 426842-85-5
4-chloro-3-fluoro-6-methoxyquinoline

Guidance literature:: With palladium 10% on activated carbon; ammonia; hydrogen; In methanol; at 2 ℃; for 2h; under 7757.43 Torr; Reagent/catalyst;
DOI:10.1016/j.bmcl.2017.06.009

Reference yield: 76.0%

: 6-methoxy-3-quinolinediazonium fluoroborate

: 426842-85-5
4-chloro-3-fluoro-6-methoxyquinoline

Guidance literature:: 6-methoxy-3-quinolinediazonium fluoroborate; In toluene; at 60 - 85 ℃; Heating / reflux;

With sodium hydroxide; In water; ethyl acetate; toluene; for 1.5h; pH=7 - 7.5;