2beta-Isopropylaziridine

Base Information

• Chemical Name: 2beta-Isopropylaziridine
• CAS No.: 45378-03-8
• Molecular Formula: C5H11N
• Molecular Weight: 85.149
• European Community (EC) Number: 896-484-3
• Nikkaji Number: J1.784.813E
• Mol file: 45378-03-8.mol

Synonyms:2beta-Isopropylaziridine;(2S)-2-propan-2-ylaziridine;45378-03-8;(2S)-2-(propan-2-yl)aziridine;AKOS006352897;EN300-7571866

Chemical Property of 2beta-Isopropylaziridine

Chemical Property:

• XLogP3: 1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 85.089149355
• Heavy Atom Count: 6
• Complexity: 49.9

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)C1CN1
• Isomeric SMILES: CC(C)[C@H]1CN1

Technology Process of 2beta-Isopropylaziridine

There total 1 articles about 2beta-Isopropylaziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

(R)-2-amino-3-methylbutanol (4276-09-9,473-75-6) → (-)-(S)-2-isopropylaziridine (45378-03-8)

Guidance literature:

With 1 M DTPP; at 60 ℃; for 48h;

DOI:10.1021/jo00351a020

Reference yield: 98.0%

Cyclohexyl isocyanate (3173-53-3) + (-)-(S)-2-isopropylaziridine (45378-03-8) → (2S)-N-cyclohexyl-2-isopropyl-aziridine-1-carboxamide

Guidance literature:

In dichloromethane; at 20 ℃; for 16h;

DOI:10.3390/molecules23010045

Reference yield: 97.0%

(-)-(S)-2-isopropylaziridine (45378-03-8) + Phenoxyacetyl chloride (701-99-5) → C13H17NO2

Guidance literature:

With triethylamine; In tetrahydrofuran; diethyl ether; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.tetasy.2014.12.005

upstream raw materials:

(R)-2-amino-3-methylbutanol

Downstream raw materials:

(S)-3-methyl-1-(phenylselanyl)butan-2-amine

(S)-N-Cbz-2-isopropylaziridine

C₂₁H₂₅NO₃S

(S)-(3,5-dinitrophenyl)(2-isopropylaziridin-1-yl)methanone