5,7-Quinolinedicarboxylic acid, 3-[(4-fluorophenyl)methyl]-8-methoxy-, 7-methyl ester

Base Information

Chemical Name:5,7-Quinolinedicarboxylic acid, 3-[(4-fluorophenyl)methyl]-8-methoxy-, 7-methyl ester
CAS No.:457949-14-3
Molecular Formula:C20H16FNO5
Molecular Weight:369.349
Hs Code.:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5,7-Quinolinedicarboxylic acid, 3-[(4-fluorophenyl)methyl]-8-methoxy-, 7-methyl ester

Chemical Property:

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Technology Process of 5,7-Quinolinedicarboxylic acid, 3-[(4-fluorophenyl)methyl]-8-methoxy-, 7-methyl ester

There total 2 articles about 5,7-Quinolinedicarboxylic acid, 3-[(4-fluorophenyl)methyl]-8-methoxy-, 7-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 457947-59-0
C₁₉H₁₅BrFNO₃

: 457949-14-3
C₂₀H₁₆FNO₅

Guidance literature:: C₁₉H₁₅BrFNO₃; With 1,3-bis-(diphenylphosphino)propane; triethylamine; palladium diacetate; In water; dimethyl sulfoxide; at 20 ℃; for 0.5h;

formaldehyd; In water; dimethyl sulfoxide; at 20 - 70 ℃; for 3h; under 760.051 Torr;

Reference yield: 78.0%

: 201230-82-2
carbon monoxide

: 457949-14-3
C₂₀H₁₆FNO₅

Guidance literature:: C₁₉H₁₅BrFNO₃; With 1,3-bis-(diphenylphosphino)propane; triethylamine; palladium diacetate; In water; dimethyl sulfoxide; at 20 ℃; for 0.5h;

carbon monoxide; In water; dimethyl sulfoxide; at 20 - 70 ℃; for 3h;

Reference yield: 94.0%

: 457949-14-3
C₂₀H₁₆FNO₅

: 141-43-5
ethanolamine

: 675614-23-0
C₂₂H₂₁FN₂O₅

Guidance literature:: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In DMF (N,N-dimethyl-formamide); at 20 ℃; for 14h;