3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Base Information

Chemical Name:3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine
CAS No.:478016-00-1
Molecular Formula:C13H16ClN3
Molecular Weight:249.743
Hs Code.:2933199090
DSSTox Substance ID:DTXSID20354375
Nikkaji Number:J1.779.124I
Wikidata:Q82132464
Mol file:478016-00-1.mol

Synonyms:478016-00-1;3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine;5-TERT-BUTYL-2-(4-CHLORO-PHENYL)-2H-PYRAZOL-3-YLAMINE;5-tert-butyl-2-(4-chlorophenyl)pyrazol-3-amine;3-TERT-BUTYL-1-(4-CHLOROPHENYL)-1H-PYRAZOL-5-AMINE;SCHEMBL1013888;DTXSID20354375;CGBTZABQTSWFJF-UHFFFAOYSA-N;MFCD02091536;AKOS005831552;AB10711;A827344;5-tert-Butyl-2-(4-chlorophenyl)-2H-pyrazol-3-amine;5-tert-butyl-2-(4-chlorophenyl)-2h-pyrazol-3-ylamine;3-tert-Butyl-1-(4-chlorophenyl)-1H-pyrazol-5-amine, AldrichCPR

Suppliers and Price of 3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Heterocyclics
3-Tert-butyl-1-(4-chlorophenyl)-1H-pyrazol-5-amine 98%
5g
$ 400.00

Heterocyclics
3-Tert-butyl-1-(4-chlorophenyl)-1H-pyrazol-5-amine 98%
1g
$ 150.00

Heterocyclics
3-Tert-butyl-1-(4-chlorophenyl)-1H-pyrazol-5-amine 98%
25g
$ 900.00

Crysdot
3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine 95+%
5g
$ 608.00

CHESS?
AP000167:5-tert-Butyl-2-(4-chloro-phenyl)-2H-pyrazol-3-ylamine 95
1 g
$ 180.00

Chemenu
5-tert-Butyl-2-(4-chloro-phenyl)-2H-pyrazol-3-ylamine 95+%
1g
$ 387.00

Chemenu
5-tert-Butyl-2-(4-chloro-phenyl)-2H-pyrazol-3-ylamine 95+%
500mg
$ 315.00

American Custom Chemicals Corporation
5-TERT-BUTYL-2-(4-CHLORO-PHENYL)-2H-PYRAZOL-3-YLAMINE 95.00%
5MG
$ 500.01

Alichem
3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine
5g
$ 504.90

Acrotein
3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine 97%
1g
$ 165.00

Total 11 raw suppliers

Chemical Property of 3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Chemical Property:

PSA：43.84000
LogP:3.98660
XLogP3:3.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:249.1032752
Heavy Atom Count:17
Complexity:256

Purity/Quality:

97% ^*data from raw suppliers

3-Tert-butyl-1-(4-chlorophenyl)-1H-pyrazol-5-amine 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xn
Statements: 22

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)C1=NN(C(=C1)N)C2=CC=C(C=C2)Cl

Technology Process of 3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

There total 4 articles about 3-(tert-Butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 59997-51-2
trimethylacetylacetonitrile

: 1073-70-7
4-chlorophenylhydrazine hydrochloride

: 478016-00-1
3-(tert-butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Guidance literature:: In ethanol; at 80 ℃;
DOI:10.3390/molecules21050677

Reference yield:

: 59997-51-2
trimethylacetylacetonitrile

: 1073-69-4
N-4-chlorophenylhydrazine

: 478016-00-1
3-(tert-butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Guidance literature:: With acetic acid; In ethanol; for 18h; Heating;
DOI:10.1016/S0960-894X(00)00272-9

Reference yield:

: 598-98-1
Methyl pivalate

: 1073-69-4
N-4-chlorophenylhydrazine

: 75-05-8,26809-02-9
acetonitrile

: 478016-00-1
3-(tert-butyl)-1-(4-chlorophenyl)-1H-pyrazol-5-amine

Guidance literature:: Methyl pivalate; acetonitrile; With sodium hydride; In tetrahydrofuran; for 2h; Reflux;

N-4-chlorophenylhydrazine; With hydrogenchloride; In ethanol; at 160 ℃; for 0.833333h; Microwave irradiation;
DOI:10.1016/j.bmcl.2019.06.062