2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-

Base Information

Chemical Name:2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-
CAS No.:479673-55-7
Molecular Formula:C59H88O8Si
Molecular Weight:953.428
Hs Code.:

2,8,13,21,23-Tetracosapentaen-1-ol,
19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl)
methoxy]-4,10,12,18,20-pentamethyl-,
(2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-

Synonyms:

Suppliers and Price of 2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)-

There total 23 articles about 2,8,13,21,23-Tetracosapentaen-1-ol, 19-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-5,11,17-tris[(4-methoxyphenyl) methoxy]-4,10,12,18,20-pentamethyl-, (2E,4R,5R,8Z,10S,11S,12S,13Z,17R,18S,19S,20S,21Z)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 479673-33-1
(4R, [5R,] 10S, [11S,] 12S, [17R,] [18R,] [19R,] 205)-19-(TERT-BUTYLDIMETHYLSILANYLOXY)-5,11, [17-TRIS-(4-METHOXYBENZYLOXY)-4, 10,] 12,18, 20-pentamethyltetracosa-2,8, 13, 21,23-pentaenoic acid ethyl ester

: 479673-55-7
(2E,8Z,13Z,21Z)-(4R,5R,10S,11S,12S,17R,18S,19S,20S)-19-(tert-Butyl-dimethyl-silanyloxy)-5,11,17-tris-(4-methoxy-benzyloxy)-4,10,12,18,20-pentamethyl-tetracosa-2,8,13,21,23-pentaen-1-ol

Guidance literature:: With diisobutylaluminium hydride;
DOI:10.1021/ol026942l

Reference yield:

: 154919-93-4
(S)-4-Benzyl-3-[(2S,3R)-6-(tert-butyl-dimethyl-silanyloxy)-3-hydroxy-2-methyl-hexanoyl]-oxazolidin-2-one

: 479673-55-7
(2E,8Z,13Z,21Z)-(4R,5R,10S,11S,12S,17R,18S,19S,20S)-19-(tert-Butyl-dimethyl-silanyloxy)-5,11,17-tris-(4-methoxy-benzyloxy)-4,10,12,18,20-pentamethyl-tetracosa-2,8,13,21,23-pentaen-1-ol

Guidance literature:: Multi-step reaction with 11 steps

1.1: LiBH₄

1.2: PPTS

2.1: 92 percent / DIBAL

3.1: Dess-Martin periodinane

4.1: NaH

5.1: 84 percent / HF*pyridine

6.1: 72 percent / Dess-Martin periodinane

7.1: 74 percent / NaHMDS

8.1: 68 percent / NaCNBH₃; TMSCl

9.1: 89 percent / Dess-Martin periodinane

10.1: 48 percent / NaHMDS

11.1: 77 percent / DIBAL

With lithium borohydride; chloro-trimethyl-silane; sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; sodium cyanoborohydride; Dess-Martin periodane; pyridine hydrogenfluoride; 3.1: Dess-Martin oxidation / 4.1: Wittig-Horner reaction / 6.1: Dess-Martin oxidation / 7.1: Wittig reaction / 9.1: Dess-Martin oxidation / 10.1: Wittig reaction;
DOI:10.1021/ol026942l

Reference yield:

: 479673-49-9
(4R,5R)-tert-butyl-{3-[2-(4-methoxyphenyl)-5-methyl[1,3]dioxan-4-yl]propoxy}dimethylsilane

: 479673-55-7
(2E,8Z,13Z,21Z)-(4R,5R,10S,11S,12S,17R,18S,19S,20S)-19-(tert-Butyl-dimethyl-silanyloxy)-5,11,17-tris-(4-methoxy-benzyloxy)-4,10,12,18,20-pentamethyl-tetracosa-2,8,13,21,23-pentaen-1-ol

Guidance literature:: Multi-step reaction with 10 steps

1: 92 percent / DIBAL

2: Dess-Martin periodinane

3: NaH

4: 84 percent / HF*pyridine

5: 72 percent / Dess-Martin periodinane

6: 74 percent / NaHMDS

7: 68 percent / NaCNBH₃; TMSCl

8: 89 percent / Dess-Martin periodinane

9: 48 percent / NaHMDS

10: 77 percent / DIBAL

With chloro-trimethyl-silane; sodium hexamethyldisilazane; sodium hydride; diisobutylaluminium hydride; sodium cyanoborohydride; Dess-Martin periodane; pyridine hydrogenfluoride; 2: Dess-Martin oxidation / 3: Wittig-Horner reaction / 5: Dess-Martin oxidation / 6: Wittig reaction / 8: Dess-Martin oxidation / 9: Wittig reaction;
DOI:10.1021/ol026942l