Benzyl 3-acetylpiperidine-1-carboxylate

Base Information

Chemical Name:Benzyl 3-acetylpiperidine-1-carboxylate
CAS No.:502639-39-6
Molecular Formula:C15H19NO3
Molecular Weight:261.321
Hs Code.:2933399090
DSSTox Substance ID:DTXSID60693139
Mol file:502639-39-6.mol

Synonyms:Benzyl 3-acetylpiperidine-1-carboxylate;502639-39-6;3-Acetyl-piperidine-1-carboxylic acid benzyl ester;Benzyl3-acetylpiperidine-1-carboxylate;SCHEMBL2180966;DTXSID60693139;CXRLRAPGUPJJTN-UHFFFAOYSA-N;CVA63939;MFCD09953373;AKOS016013035;SB37371;AS-63933;CS-0272111;FT-0755869;EN300-6253663;J-519827

Suppliers and Price of Benzyl 3-acetylpiperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

J&W Pharmlab
3-Acetyl-piperidine-1-carboxylicacidbenzylester 98%
500mg
$ 198.00

Crysdot
Benzyl3-acetylpiperidine-1-carboxylate 95+%
1g
$ 668.00

American Custom Chemicals Corporation
1-N-CBZ-3-ACETYLPIPERIDINE 95.00%
5MG
$ 500.74

Total 8 raw suppliers

Chemical Property of Benzyl 3-acetylpiperidine-1-carboxylate

Chemical Property:

PSA：46.61000
LogP:2.56210
Storage Temp.:2-8°C
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:261.13649347
Heavy Atom Count:19
Complexity:323

Purity/Quality:

97% ^*data from raw suppliers

3-Acetyl-piperidine-1-carboxylicacidbenzylester 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)C1CCCN(C1)C(=O)OCC2=CC=CC=C2

Technology Process of Benzyl 3-acetylpiperidine-1-carboxylate

There total 5 articles about Benzyl 3-acetylpiperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 405239-72-7
benzyl 3-[methoxy(methyl)carbamoyl]piperidine-1-carboxylate

: 75-16-1
methylmagnesium bromide

: 502639-39-6
benzyl 3-acetylpiperidine-1-carboxylate

Guidance literature:: benzyl 3-[methoxy(methyl)carbamoyl]piperidine-1-carboxylate; methylmagnesium bromide; In diethyl ether; at 0 - 20 ℃;

With ammonium chloride; In diethyl ether; water;

Reference yield:

: 80851-96-3
1-piperidin-3-yl-ethanone

: 501-53-1,94274-21-2
benzyl chloroformate

: 502639-39-6
benzyl 3-acetylpiperidine-1-carboxylate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; for 19h;

Reference yield:

: 78190-11-1
1-benzyloxycarbonylpiperidine-3-carboxylic acid

: 502639-39-6
benzyl 3-acetylpiperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 2 - 20 °C

2: diethyl ether / 0 - 20 °C

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In diethyl ether; dichloromethane;